The Impact of Ethanol Sclerotherapy Before ART (Assisted Reproductive Technology) Cycle on Cumulative Live Birth Rate in Infertile Women With Endometrioma: A Randomized Controlled Trial

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this randomized controlled trial is to assess the impact of ethanol sclerotherapy on ART cycle outcomes. The main questions it aims to answer are: 1. Does ethanol sclerotherapy before ART cycle has any impact on cumulative live birth rate in patients with endometrioma? 2. Does ethanol sclerotherapy improve chronic pelvic pain, dysmenorrhea, complications during oocyte retrieval, response to ovarian stimulation (number of mature oocytes retrieved), and pregnancy loss rates? Infertile patients with endometrioma between 4-10 cm who are scheduled for ART within 2 cycles will be randomized to ethanol sclerotherapy or no intervention.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 40
Healthy Volunteers: t
View:

• AMH\>0.3 ng/ml

• unilateral/bilateral endometrioma

• Endometrioma diameter 40-100 mm

Locations
Other Locations
Turkey
Başkent University Adana IVF Center
RECRUITING
Adana
Ankara University School of Medicine, Department of Obstetrics and Gynecology
RECRUITING
Ankara
Bahçeci IVF Clinic
RECRUITING
Istanbul
Contact Information
Primary
Yavuz Emre Sukur
yesukur@gmail.com
+905332409381
Backup
Sezcan Mumusoglu
sezcanmumusoglu@gmail.com
+905326404673
Time Frame
Start Date: 2023-05-01
Estimated Completion Date: 2026-04-01
Participants
Target number of participants: 84
Treatments
No_intervention: Control
In eligible patients allocated to control group, no interventions will be done before ART cycle.
Experimental: Ethanol sclerotherapy
In eligible patients allocated to study group, endometrioma/s will be aspirated and treated with ethanol for 10 minutes 1-2 cycles before ART.
Related Therapeutic Areas
Sponsors
Leads: Ankara University
Collaborators: Hacettepe University

This content was sourced from clinicaltrials.gov