Balloon-occluded Retrograde Transvenous Obliteration Versus Endoscopic Tissue Glue Injection in the Prevention of Recurrent Gastric Variceal Bleeding

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

The goal of this randomized controlled trial is to compare the rebleeding rate in cirhotic patients with gastric variceal bleeding receiving balloon-occluded retrograde transvenous obliteration and endoscopic tissue glue injection. The main questions it aims to answer are: * Recurrent gastric variceal bleeding * Further decompensation of liver cirrhosis Participants will receive balloon-occluded retrograde transvenous obliteration and endoscopic tissue glue injection. Researchers will compare balloon-occluded retrograde transvenous obliteration and endoscopic tissue glue injection to see if the rebleeding rate associated with balloon-occluded retrograde transvenous obliteration is lower than that associated with endoscopic tissue glue injection.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Healthy Volunteers: f
View:

• age more than 20 years

• a history of liver cirrhosis

• acute GOV2 or IGV1 bleeding

Locations
Other Locations
Taiwan
Kaohsiung Veterans General Hospital
RECRUITING
Kaohsiung City
Contact Information
Primary
Wen-Chi Chen, M.D
wcchen@vghks.gov.tw
+886 (07) 3468016
Time Frame
Start Date: 2018-06-28
Estimated Completion Date: 2025-06
Participants
Target number of participants: 68
Treatments
Experimental: Balloon-occluded retrograde transvenous obliteration
Information of drug:~3% sodium tetradecyl sulfate injection Name: Fibro-vein injection Manufacturer: STD Pharmaceutical Products Ltd.
Active_comparator: Endoscopic cyanoacrylate injection
Information of drug:~N-butyl-2-cyanoacrylate Name: Histoacryl blue Manufacturer: Braun, Melsungen, Germany
Sponsors
Leads: Kaohsiung Veterans General Hospital.

This content was sourced from clinicaltrials.gov