INTO-HLH- Insight Into the Natural History and Treatment Outcomes of Hemophagocytic Lymphohistiocytosis (HLH): A Disease Registry for Patients With HLH
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The purpose of this observational study is to collect data on the natural history of disease of patients with Hemophagocytic Lymphohistiocytosis (HLH) including diagnosis, treatments, responses, and outcomes.
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• Patients with clinically suspected or confirmed HLH, including those meeting the HLH-2004 diagnostic criteria (primary or secondary forms, including malignancy) and other forms of HLH (macrophage activation syndrome \[MAS\], cytokine release syndrome \[CRS\], etc.)
• Signed and dated informed consent and assent (adolescents)
Locations
United States
Ohio
Cincinnati Children's Hospital Medical Center
RECRUITING
Cincinnati
Contact Information
Primary
Michael Jordan, MD
Michael.Jordan@cchmc.org
(513) 803-9063
Backup
Adi Zoref Lorenz, MD
Adi.Zoref.Lorenz@cchmc.org
Time Frame
Start Date: 2021-12-31
Estimated Completion Date: 2026-01
Participants
Target number of participants: 200
Treatments
Patients with clinically suspected or confirmed Hemophagocytic Lymphohistiocytosis
Multi-institutional cohort registry of patients with clinically suspected or confirmed Hemophagocytic Lymphohistiocytosis
Related Therapeutic Areas
Sponsors
Collaborators: Sobi, Inc., Baylor College of Medicine
Leads: Children's Hospital Medical Center, Cincinnati