68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling to Determine Treatment in Primary Aldosteronism: A Multicenter Randomized Clinical Trial
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
To compare the 68Ga-Pentixafor PET/CT and adrenal vein sampling on the long-term outcomes of primary aldosteronism (PA) patients with adrenal nodule (≥1cm)
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:
• (1)Getting the written informed consent (2)ARR ≥20 (pg/ml)/ (μIU/ml) or ARR ≥ 30(ng/dL)/(ng/ml/hr) plus at least one positive PA confirmatory test (CCT, SSIT).
Locations
Other Locations
China
The First Affilated Hospital of Chongqing Medical University
RECRUITING
Chongqing
Contact Information
Primary
Qifu Li, PhD
liqifu@yeah.net
+86 023-89011552
Time Frame
Start Date: 2024-01-09
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 320
Treatments
Experimental: 68Ga-Pentixafor PET/CT group
Patients divided into 68Ga-Pentixafor PET/CT group need to undergo 68Ga-Pentixafor PET/CT examination and guide subsequent treatment based on the results
No_intervention: AVS group
Patients divided into AVS group need to undergo AVS to guide subsequent treatment based on the results
Related Therapeutic Areas
Sponsors
Collaborators: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Second Affiliated Hospital, School of Medicine, Zhejiang University, The First Affiliated Hospital of Zhengzhou University, West China Hospital, The Affiliated Hospital Of Southwest Medical University, Tongji Hospital, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, Changzhi Medical College
Leads: Qifu Li