The Development and Validation of Quantitative Imaging Biomarkers as a Measure of Disease Activity in Juvenile Idiopathic Arthritis
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
This observational study aims to develop and validate quantitative magnetic resonance imaging biomarkers as measures of disease activity in juvenile idiopathic arthritis (JIA). This includes patients with enthesitis-related arthritis (ERA).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 12
Maximum Age: 24
Healthy Volunteers: t
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• Participant is willing and able to give informed consent for participation in the study.
• For cases, patients will have clinical diagnosis of JIA: enthesitis-related arthropathy, extended oligoarthritis or polyarthritis (defined according to ILAR criteria)
• For controls, patients will have a diagnosis of mechanical back pain (though to arise from muscles, bones, ligaments or discs), with normal inflammatory markers
• Age 12-24
Locations
Other Locations
United Kingdom
University College London Centre for Medical Imaging
RECRUITING
London
Contact Information
Primary
Timothy JP Bray, MBBChir
t.bray@ucl.ac.uk
0203 447 9324
Time Frame
Start Date: 2016-01
Estimated Completion Date: 2026-01
Participants
Target number of participants: 200
Treatments
Group A
Patients with enthesitis-related arthritis
Group B
Patients with other forms of juvenile idiopathic arthritis (extended oligoarticular JIA and polyarticular JIA)
Related Therapeutic Areas
Sponsors
Leads: University College London Hospitals