Establishment of Clinical Basis for Hematopoietic Growth Factors Therapy in Brain Injury

Who is this study for? Patients with Neurological Diseases
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY

The purpose of our study is to determine the safety and efficacy of the combination of erythropoietin (EPO) and granulocyte-colony stimulating factors (G-CSF) in patients with neurological diseases. To be specific, our clinical study is expected that the combination injection of EPO and G-CSF shows neurotrophic and neuroprotective effects by facilitating endogenous repair process in patients with neurological diseases including stroke, cerebral palsy, or atypical parkinsonism. Therefore, we will apply our original treatment technique in patients with neurological diseases, which is expected to overcome current ethical and technical limitations of less evidenced functional recovery, hematological changes, and side effects. Eventually, We will establish a comprehensive clinical background about neurotrophic and neuroprotective effects of this hematopoietic growth factors therapy.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Healthy Volunteers: f
View:

• Over 20 years old

• Voluntary participants

• Neurological diseases including stroke, cerebral palsy, or atypical parkinsonism, at least 3 months after their onset

• Participants who got previous EPO+GCSF injection at least 6 months ago.

Locations
Other Locations
Republic of Korea
Department of Rehabilitation Medicine, Yonsei University College of Medicine
RECRUITING
Seoul
Contact Information
Primary
Sung-Rae Cho, MD
srcho918@yuhs.ac
82-2-2228-3715
Time Frame
Start Date: 2011-07-05
Estimated Completion Date: 2025-12
Participants
Target number of participants: 60
Treatments
Experimental: Intervention
Intervention Group
Placebo_comparator: Control
Control Group
Sponsors
Leads: Yonsei University

This content was sourced from clinicaltrials.gov