Virtual Surgery of the Upper Airways-New Solutions to Obstructive Sleep Apnea Treatment

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

Obstructive sleep apnea (OSA) is a sleep related breathing disorder caused by repetitive collapses of the upper airways resulting in impaired breathing, oxygen desaturation and sleep disturbances. OSA has a massive impact on global health contributing directly to cardiovascular diseases, insulin resistance, metabolic syndrome and daytime fatigue and is repeatedly associated with an increase in motor vehicle accidents. The mainstay of treatment is still the use of positive airway pressure or surgery of the upper airways, but the success rate is persistently low. Surgery may be of help, but there is a lack of patient-specific options in both diagnostics and treatment. Mathematical and computational modeling is expected to provide significant insight into the airway function and onset of OSA. This study is part of a project that will rely on biomedical engineering to obtain the required insight to produce software tools for computer-aided diagnostics and treatment of OSA.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Obstructive sleep apnea

• need either functional septorhinoplasty or oropharyngeal/orthognathic surgery in order to establish adequate airway patency

• have undergone sleep registration using polysomnography and ultrawideband radar

• on the subsequent clinical evaluation presenting either 1) intranasal obstruction, due to malalignment of the nasal septal cartilage or the nasal outer framework; and/or 2) oropharyngeal obstruction or retrognathia.

Locations
Other Locations
Norway
Aleris Solsiden
RECRUITING
Trondheim
St Olavs Hospital
RECRUITING
Trondheim
Contact Information
Primary
Mads HS Moxness, md phd
madsmox@gmail.com
+47 99035515
Backup
Ståle Nordgård, phd prof
stale.nordgard@ntnu.no
0047 72880232
Time Frame
Start Date: 2021-04-20
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 30
Treatments
Obstructive sleep apnea (OSA)
OSA patients who are eligible for either functional septorhinoplasty or oropharyngeal/orthognathic surgery
Sponsors
Collaborators: St. Olavs Hospital, SINTEF Health Research
Leads: Norwegian University of Science and Technology

This content was sourced from clinicaltrials.gov