Assessment of Corneal Endothelial Function Following Hypoxic Stress
The purpose of this study is to determine the difference in the cornea's response to contact lens placement between healthy and unhealthy eyes. The amount of corneal swelling (corneal thickness) between normal and FECD patients before and after a stress test will be measured and compared.
⁃ Subjects in the Fuch's Dystrophy arm of the study must meet following criteria:
• Have a clinical diagnosis of Fuchs endothelial corneal dystrophy
• Be scheduled for corneal transplantation in the next 6 months
• Have no history of prior ocular surgery in study eye
• Have no history of contact lens intolerance
• Be motivated and willing to complete ocular imaging tests
⁃ Subjects in the healthy eyes arm of the study must meet following criteria:
• Have no prior history of ocular disease including ocular surface disease or glaucoma
• Have no history of prior ocular surgery in study eye
• Have no history of contact lens intolerance
• Be motivated and willing to complete ocular imaging tests