Evaluating Corneal Edema in Fuchs' Endothelial Dystrophy Using Optical Coherence Tomography
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
This is an observational study using optical coherence tomography (OCT) technology to quantify corneal edema in Fuchs' endothelial dystrophy and predict refractive shift from resolving corneal edema after surgical treatments.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Damaged or diseased corneal endothelium from Fuchs' or PBK
• Willingness to commit to required study visits
Locations
United States
Oregon
Oregon Health & Science University
RECRUITING
Portland
Contact Information
Primary
Humberto Martinez, COT
martinhu@ohsu.edu
503-494-7712
Backup
Denzil Romfh, OD
romfhd@ohsu.edu
503-494-4351
Time Frame
Start Date: 2020-06-26
Estimated Completion Date: 2028-06
Participants
Target number of participants: 60
Treatments
Group A: No Surgery Group
This group consists of adults ages 18 or older who have been diagnosed with Fuchs' dystrophy or pseudophakic bullous keratopathy but do not require surgery per standard-of-care guidelines.
Group B: Surgery Group
This group consists of adults ages 18 or older who have been diagnosed with Fuchs' dystrophy or pseudophakic bullous keratopathy, who require Descemet's Stripping Endothelial Keratoplasty (DSAEK), Descemet's Membrane Endothelial Keratoplasty (DMEK), or Descemet's Stripping Only (DSO) surgery. All treatment decisions will be made by the attending physician based on standard-of-care guidelines. (The study does not designate a treatment modality or pay for the treatment.)
Related Therapeutic Areas
Sponsors
Collaborators: National Eye Institute (NEI)
Leads: Oregon Health and Science University