Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France. The French Fuchs' Follow-up Study (Phase 2), F3S2
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test, Genetic, Other
Study Type: Observational
SUMMARY
The pathophysiology of the most common corneal endothelial dystrophies (Fuchs' Corneal Endothelial Dystrophy, FECD) is beginning to be dismembered. There is a significant heterogeneity in the clinical forms and the investigators have just highlighted a great diversity of histological forms that seem to define distinct groups.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• affiliated with or entitled to a social security scheme
• Consent form to participate in the study signed
• with an FECD certified by slit lamp examination
• requiring an endothelial keratoplasty
Locations
Other Locations
France
CHU Saint-Etienne
RECRUITING
Saint-etienne
Contact Information
Primary
GILLES THURET, MD-PhD
gilles.thuret@univ-st-etienne.fr
(0)477127793
Backup
PHILIPPE GAIN, MD-PhD
philippe.gain@chu-st-etienne.fr
0477127793
Time Frame
Start Date: 2024-08-08
Estimated Completion Date: 2026-06-01
Participants
Target number of participants: 500
Treatments
Patients with FECD
Patients with Fuchs Endothelial Corneal Dystrophy (FECD). They will have a collection of data and a blood sample
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier Universitaire de Saint Etienne
Collaborators: Kyoto University, Graduate School of Medicine