Gastroparesis Clinical Trials

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Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy: a Multicentre Prospective Cohort Study

Status: Recruiting
Location: See all (3) locations...
Study Type: Observational
SUMMARY

Gastric retention not only compromises the quality of endoscopic examination but also significantly increases the risk of reflux and aspiration in sedated patients. Aspiration of gastric contents represents a critical anesthesia-related complication during the perioperative period, carrying substantial implications for anesthetic management. With the growing volume of sedated gastroscopy procedures, predicting gastric retention has become an urgent clinical priority. This prospective study aims to establish a standardized gastric residual volume (GRV) grading system to evaluate both the volume of retained gastric contents and its contributing factors in patients undergoing upper gastrointestinal endoscopy. We will systematically assess the impact of demographic characteristics, comorbidities, and medication history on gastric emptying function. This study will facilitate establishment of an endoscopy-based simplified assessment system for gastric retention.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age ≥18 years.

• Patients scheduled for elective sedated gastroscopy or sedated gastro-colonoscopy.

• Participant provides informed consent.

Locations
Other Locations
China
The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING
Hangzhou
The Second Affiliated Hospital of Jiaxing University
RECRUITING
Jiaxing
The Fifth Affiliated Hospital of Wenzhou Medical University
NOT_YET_RECRUITING
Lishui
Contact Information
Primary
Diansan Su, Chief Physician
diansansu@yahoo.com
+8618616514088
Backup
Mingxia Xu
xumingxia@zju.edu.cn
+8613516713435
Time Frame
Start Date: 2025-08-03
Estimated Completion Date: 2026-05-31
Participants
Target number of participants: 5000
Treatments
Model Development Cohort, External Validation Cohort
Model Development Cohort Definition: 3,000 patients used to identify risk factors and build the prediction mode.~External Validation Cohort Definition: 2,000 independent patients from multiple centers to test the model's accuracy.
Sponsors
Leads: Zhejiang University

This content was sourced from clinicaltrials.gov