The Role and Mechanism of SphK1/S1P/FOXO1 Axis Regulating KATP Channel Mediated Gastric Smooth Muscle Dysfunction in Diabetes Gastroparesis
This study is a prospective observational study. The study will explore the correlation between advanced glycation end products and gastric motility disorder in diabetic gastroparesis（DGP) through the collection of blood and gastric tissue samples and relevant data of patients with DGP and control group patients without diabetes history and gastroparesis symptoms.
• Meet the diagnostic criteria for diabetes
• Presence of symptoms (see assessment of Gastroparesis Cardinal Symptom Index)
• Age range from 18 to 75 years old
• Voluntarily participate and sign an informed consent form
• No history of diabetes
• No symptoms (see assessment of Gastroparesis Cardinal Symptom Index)
• Age range from 18 to 75 years old
• Voluntarily participate and sign an informed consent form