Role of the Environment and Endocrine Disruptors in Child Cryptorchidism

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Cryptorchidism is the most frequent congenital defect of the male newborn. It requires surgery in childhood, increases the risk of fertility disorders and cancer. As a major public health objective, it's the subject of numerous recommendations. Its frequency is increasing in some countries faster than a single genetic cause could not explain it. It may occurs in a geographic cluster. The cause of cryptorchidism involves genetic, hormonal and environmental factors. Animal studies suggest that endocrine disruptors interfere with fetal testicular migration. The aim of the study is to find out if some environmental exposition may be associated with cryptorchidism.

Eligibility
Participation Requirements
Sex: Male
Minimum Age: 1 month
Maximum Age: 18
Healthy Volunteers: f
View:

• \- Parents of male children from the neonatal period to 18 years of age (during surgery) with cryptorchidism

Locations
Other Locations
France
University hospital of Montpellier
RECRUITING
Montpellier
Contact Information
Primary
Nicolas KALFA, MD
n-kalfa@chu-montpellier.fr
00334 67 33 87 84
Time Frame
Start Date: 2020-04-16
Estimated Completion Date: 2028-04-15
Participants
Target number of participants: 1452
Treatments
Parent of patient with cryptorchidism
parent exposition of endocrine disruptors
Parent of patient without cryptorchidism
Parent exposition of endocrine disruptors
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Montpellier
Collaborators: University Hospital, Bordeaux

This content was sourced from clinicaltrials.gov