Evaluation of Minipuberty in Infants Born With a Variation in Sexual Development
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Disorders of sex development (DSD) occur in 1/3000 births and are defined by variation in aspect of external genital organs, e.g. cryptorchidism, hypospadias and micropenis in male infants and clitoral hypertrophy in female infants. Genetic, hormonal and environmental factors are implicated in DSD. Infants with congenital hypogonadism hypogonadotrope (CHH) can present with DSD. Evaluation of hormonal profile during minipuberty could be of great help to better characterize the etiology of DSD and CHH in particular. Our main objective is to study hormonal profile during the minipuberty of infants born with DSD or born from parents with CHH compared to controls.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 9 months
Healthy Volunteers: t
View:
• infants born with symptoms of DSD
• infants born from parents with CHH
Locations
Other Locations
Switzerland
Centre Hospitalier Universitaire Vaudois (CHUV)
RECRUITING
Lausanne
Contact Information
Primary
Nelly Pitteloud, MD
nelly.pitteloud@chuv.ch
+41 79 556 27 36
Backup
Research assistant
edm.biobank@chuv.ch
+41 (0)79 556 37 50
Time Frame
Start Date: 2017-01-01
Estimated Completion Date: 2030-12-31
Participants
Target number of participants: 100
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier Universitaire Vaudois