Urothelial Cancer

Condition 101

What is the definition of Urothelial Cancer?

Urothelial cancer, also known as transitional cell carcinoma, affects the kidney (renal) pelvis or ureter (tube) that drains urine from the kidney to the bladder and/or the lining of the inside of the bladder. It is the most common form of bladder cancer and occurs more frequently in men and older adults. The cause of urothelial cancer is unknown; however, some suspected causes are chronic irritation of the kidney from pain medicines, exposure to manufacturing chemicals and dyes, smoking or other tobacco use, past radiation exposure, and parasitic infections.

What are the symptoms for Urothelial Cancer?

Symptoms of urothelial cancer include fatigue, unexplained weight loss, loss of appetite, anemia, constant back pain, flank pain, pelvic pain, urinary urgency, pain, burning, or discomfort when urinating, or blood in urine (hematuria).

What are the current treatments for Urothelial Cancer?

Treatment for urothelial cancer includes surgery and chemotherapy. Bladder cancer can recur after treatment; therefore, long-term follow-up is necessary.

Latest Research

Latest Advance
  • Condition: Miliary Pulmonary Tuberculosis
  • Journal: Revue medicale de Liege
  • Treatment Used: Intravesical Bacillus Calmette-Guerin (BCG) Instillation therapy
  • Number of Patients: 1
  • Published —
This case report describes a 74-year-old male who developed pulmonary granulomatosis secondary to intravesical Bacillus Calmette-Guerin (BCG) instillation therapy.
Latest Advance
  • Condition: Patients with Renal Insufficiency and Mixed Variant Histology (MVH)
  • Journal: Journal for immunotherapy of cancer
  • Treatment Used: Atezolizumab
  • Number of Patients: 218
  • Published —
This study reported the safety and effectiveness of atezolizumab in patients with renal insufficiency or urothelial carcinoma (UC) with mixed variant histology (MVH).
Latest Advance
  • Condition: Advanced or Metastatic Urothelial Cancer
  • Journal: Anticancer research
  • Treatment Used: Second-Line Chemotherapy
  • Number of Patients: 25
  • Published —
This study assessed the effectiveness of second-line chemotherapy in patients with advanced or metastatic urothelial cancer.
Latest Advance
  • Condition: Tumors
  • Journal: Annals of oncology : official journal of the European Society for Medical Oncology
  • Treatment Used: Nivolumab once every 4 weeks
  • Number of Patients: 3203
  • Published —
The study researched the effects of Nivolumab once every 4 weeks for many different types of tumors.