What is the definition of Urothelial Cancer?

Urothelial cancer, also known as transitional cell carcinoma, affects the kidney (renal) pelvis or ureter (tube) that drains urine from the kidney to the bladder and/or the lining of the inside of the bladder. It is the most common form of bladder cancer and occurs more frequently in men and older adults. The cause of urothelial cancer is unknown; however, some suspected causes are chronic irritation of the kidney from pain medicines, exposure to manufacturing chemicals and dyes, smoking or other tobacco use, past radiation exposure, and parasitic infections.

What are the symptoms for Urothelial Cancer?

Symptoms of urothelial cancer include fatigue, unexplained weight loss, loss of appetite, anemia, constant back pain, flank pain, pelvic pain, urinary urgency, pain, burning, or discomfort when urinating, or blood in urine (hematuria).

What are the current treatments for Urothelial Cancer?

Treatment for urothelial cancer includes surgery and chemotherapy. Bladder cancer can recur after treatment; therefore, long-term follow-up is necessary.
  • Condition: Upper Tract Urothelial Carcinoma (UTUC)
  • Journal: Investigative and clinical urology
  • Treatment Used: Nephron-Sparing Management
  • Number of Patients: 0
  • Published —
This review of the literature examined nephron-sparing treatments for patients with urothelial carcinoma of the upper urinary tract (UTUC).
  • Condition: Muscle-Invasive Bladder Cancer (MIBC)
  • Journal: Frontiers in immunology
  • Treatment Used: Chemotherapy Combined with Immunotherapy
  • Number of Patients: 1
  • Published —
This case report describes a 50-year-old male diagnosed with muscle-invasive bladder cancer (MIBC) treated with chemotherapy combined with immunotherapy.