Medical Treatment Alone Versus Varicocelectomy Versus Varicocelectomy and Medical Treatment in Management of Male Subfertility With Isolated Teratozoospermia: A Prospective Randomized Study
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
A varicocele is defined as an abnormal venous dilatation and/or tortuosity of the pampiniform plexus in the scrotum. Although varicoceles are almost always and more common on the left side, up to 50% of the men with varicocele, have bilateral varicoceles. Varicocele has a negative impact on spermatogenesis, testicular volume, Standard semen parameters, and fertilization, implantation, and embryo outcomes.
Eligibility
Participation Requirements
Sex: Male
Minimum Age: 20
Maximum Age: 50
Healthy Volunteers: f
View:
• Sub-fertile men with clinically palpable varicoceles ( unilateral or bilateral ).
• Men with teratozoospermia.
Locations
Other Locations
Egypt
South Valley University Hospital
RECRUITING
Qina
Contact Information
Primary
Marwan Mohamed Ali Bastawy, Resident
marwan13156@gmail.com
+201066067330
Time Frame
Start Date: 2024-09-01
Estimated Completion Date: 2025-08-31
Participants
Target number of participants: 126
Treatments
Active_comparator: Group of l-carnitine and antioxidant
About 42 male patients suffering from teratozoospermia will take medical treatment (l-carnitine and antioxidant) once daily for 3 months
Active_comparator: Group of varicocelectomy
About 42 male patients suffering from teratozoospermia will undergo subinguinal varicocelectomy.
Active_comparator: Group of Mixed Treatment(varicocelectomy then l-carnitine and antioxidant)
About 42 male patients suffering from teratozoospermia will undergo subinguinal varicocelectomy then adjuvant treatment (l-carnitine and antioxidant) for 3 months.
Related Therapeutic Areas
Sponsors
Leads: South Valley University