A Randomized Post-Market Study Assessing Complete Wound Healing by Comparing Surgenex® PelloGraft in Treating Diabetic Foot Ulcers (DFU) and SanoGraft® in Treating Venous Leg Ulcers (VLU) to SOC Treatment

Status: Recruiting
Location: See all (4) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to compare Pellograft to standard of care modalities in treating diabetic foot ulcers in human subjects, and to compare Sanograft to standard of care in treating venous leg ulcers. The study will demonstrate wound healing outcomes with comparators including time to wound epithelialization, decrease in wound size, and total number of study product applications towards healing outcome. This information is important to the Centers for Medicare and Medicaid Services (CMS) and other payors in determining coverage policy and reimbursement for this product category.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Subject is at least 18 years of age

• Diabetic Foot Ulcer Only - Subject has diagnosed Type 1 or Type 2 diabetes

• Subject's wound is located on foot or ankle (DFU) or leg (VLU)

• Subject has diabetic foot ulcer \> 1.0 cm2 and ≤ 25 cm2 OR venous leg ulcer \> 1.0 cm2 and ≤ 50 cm2

• Subject has adequate circulation to affected extremity with TcPO2 results of ≥ 40 mm Hg on the dorsum of the affected foot or ABI results ≥ 0.7 and≤ 1.2 or Great Toe Pressure ≥ 50 mmHg

• Subject is willing and able to comply with all protocol requirements

• Subject is willing and able to provide informed consent or obtain consent from legal authorized representative (LAR)

Locations
United States
California
ILD Research
RECRUITING
Vista
Florida
Future Life Clinical Trials
RECRUITING
North Miami
Massachusetts
Boston Medical Center
RECRUITING
Boston
Oklahoma
Essential Medical Research
RECRUITING
Tulsa
Contact Information
Primary
Pam McKeown
pamela.mckeown@surgenex.com
480-404-3143
Time Frame
Start Date: 2024-06-23
Estimated Completion Date: 2026-09-09
Participants
Target number of participants: 180
Treatments
Experimental: Arm 1 PelloGraft
PelloGraft treatment for diabetic foot ulcers versus Standard of Care treatment for diabetic foot ulcers
Experimental: Arm 2 SanoGraft
SanoGraft treatment for venous leg ulcers vs Standard of Care treatment for venous leg ulcers
Related Therapeutic Areas
Sponsors
Leads: Surgenex

This content was sourced from clinicaltrials.gov