Development of a Risk Stratification Score for Recurrent Venous Thromboembolism and Treatment-related Clinically Relevant Bleeding in Patients With Cancer-associated Thrombosis

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The objective of this study is to prospectively develop a risk assessment model (RAM) that accurately identifies anticoagulated cancer-associated thrombosis (CAT) patients at low- and high-risk of recurrent venous thromboembolism (VTE) and clinically relevant bleeding within 6 months following the CAT diagnosis and to create a biobank of plasma and whole blood samples for further translational research in cancer genetics and hemostasis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Objectively documented distal and/or proximal DVT of the limb (upper or lower extremity) and/or PE, splanchnic vein thrombosis and/or cerebral sinus vein thrombosis in presence of active cancer of all types

• Intended treatment of CAT for at least 6 months with parenteral or oral anticoagulants at therapeutic dosing.

• Estimated life expectancy \> 6 months

• Willingness to give an informed consent

• Age ≥ 18 years

Locations
Other Locations
Canada
Ottawa Hospital Research Institute
RECRUITING
Ottawa
Contact Information
Primary
Kristina Vrotniakaite-Bajerciene, MD
kvrotniakaite@toh.ca
613-737-8899
Time Frame
Start Date: 2024-12-03
Estimated Completion Date: 2027-12
Participants
Target number of participants: 1000
Sponsors
Collaborators: Canadian Institutes of Health Research (CIHR)
Leads: Ottawa Hospital Research Institute

This content was sourced from clinicaltrials.gov