Effect of Procyanidins in the Leaky Gut Repairing Associated with Inflammatory Bowel Disease

Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if the Grape Seed Extract Ecovitis, featuring low monomeric catechins content and a high concentration of oligo-polymeric procyanidins, could modulate the Gut Microbiota composition of Ulcerative Colitis patients during the remission phase. The main questions it aims to answer are: Does Ecovitis improve the microbiota composition in patients with Ulcerative colitis? Is the intestinal permeability affected? What about the variation in the quality of life? Participants will: Take 2 capsules/day of Ecovitis for eight weeks Visit the clinic two times for checkups, serum collection, and Questionaire.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Diagnosis of UC confirmed by clinical, endoscopic and histopathological evidence. Disease in remission phase confirmed by clinical, endoscopic and histopathological evidence.

‣ Age between 18 and 75 years old

⁃ Ability of subject to participate fully in all aspects of this clinical trial.

Locations
Other Locations
Italy
Edoardo Vincenzo Savarino
RECRUITING
Padua
Contact Information
Primary
Edoardo V. Savarino, MD; PhD
edoardo.savarino@unipd.it
0498218720
Backup
Sonia Facchin, PhD
sonia.facchin@unipd.it
0498218720
Time Frame
Start Date: 2024-06-15
Estimated Completion Date: 2026-06-12
Participants
Target number of participants: 25
Treatments
Experimental: Active supplement
Treatment: the capsules contains Grape Seed Extract GSE-0001- Proanthocyanidins \<95%)
Sponsors
Leads: University of Padova

This content was sourced from clinicaltrials.gov

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