The Efficacy and Safety of Oral Mini-pulse Dexamethasone in Active Non-segmental Vitiligo Within the Pediatric Age Group

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

The goal of this clinical trial is to learn if oral mini pulse (OMP) dexamethasone works to treat active vitiligo in children and also learn about the safety of this drug within this age group the main questions it aims to answer are does OMP halt activity in active vitiligo and what medical problems patients might experience while using the drug with special attention to linear growth. Researchers will give OMP dexamethasone to participating patients to see if the drug works to treat active vitiligo and whether it has any effect on linear growth. Participants will take OMP dexamethasone two fixed days per week for a period of 3 months. before starting treatment, patients will do baseline evaluation and investigations then monthly evaluation to monitor progress, report any side effects at the end of treatment period response to drug, lab values and growth will be evaluated then final evaluation of growth will be done after stoppage of drug.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 4
Maximum Age: 9
Healthy Volunteers: f
View:

• Active (VIDA +3 \& +4) non segmental vitiligo

• Age between 4-9yrs

• Males and Females

• Children with height measurements within the percentile range 5-95% of normal values for their age.

Locations
Other Locations
Egypt
Dermatology Outpatient Clinic, Kasr al Ainy Teaching Hospital, Cairo University
RECRUITING
Cairo
Contact Information
Primary
Nanis Ragab, MD
nanisragab@kasralainy.edu.eg
+2 1227449161
Time Frame
Start Date: 2026-01
Estimated Completion Date: 2026-06
Participants
Target number of participants: 22
Treatments
Experimental: OMP dexamethasone 2 consecutive days per week in a dose of 0.1mg/kg/day for 3 months
Related Therapeutic Areas
Sponsors
Leads: Cairo University

This content was sourced from clinicaltrials.gov