Werner Syndrome Latest Advances

Find the Latest Research About Werner Syndrome

Last Updated: 06/30/2026

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Found 1710 publications

Structure-Guided Discovery of Potent, Selective, and Orally Bioavailable Werner Syndrome RecQ Helicase Inhibitors for the Treatment of Microsatellite Instability-High Tumors.

Structure-Guided Discovery of Potent, Selective, and Orally Bioavailable Werner Syndrome RecQ Helicase Inhibitors for the Treatment of Microsatellite Instability-High Tumors.

Journal: Journal of medicinal chemistry

Published: June 03, 2026

Design of Cyclic Vinyl Sulfones as WRN Covalent Inhibitors from Noncovalent Binders.

Design of Cyclic Vinyl Sulfones as WRN Covalent Inhibitors from Noncovalent Binders.

Journal: Journal of medicinal chemistry

Published: April 29, 2026

George Martin and Werner syndrome.

George Martin and Werner syndrome.

Journal: Cytogenetic and genome research

Published: April 06, 2026

Ocular Manifestations in Patients with Werner Syndrome.

Ocular Manifestations in Patients with Werner Syndrome.

Journal: International journal of molecular sciences

Published: March 05, 2026

The Werner syndrome RECQ helicase as a therapeutic target: new insights.

The Werner syndrome RECQ helicase as a therapeutic target: new insights.

Journal: Expert opinion on therapeutic targets

Published: January 20, 2026

Innervated superficial circumflex iliac artery perforator flap for refractory elbow ulcer with bone exposure in Werner syndrome: A case report.

Innervated superficial circumflex iliac artery perforator flap for refractory elbow ulcer with bone exposure in Werner syndrome: A case report.

Journal: JPRAS open

Published: January 18, 2026

Discovery and Preclinical Evaluations of Potent, Selective, and Allosteric Covalent WRN Inhibitors with Improved PK Properties.

Discovery and Preclinical Evaluations of Potent, Selective, and Allosteric Covalent WRN Inhibitors with Improved PK Properties.

Journal: ACS medicinal chemistry letters

Published: December 31, 2025

Novel Werner Syndrome RecQ DNA Helicase (WRN) Inhibitors for Cancer Treatment.

Novel Werner Syndrome RecQ DNA Helicase (WRN) Inhibitors for Cancer Treatment.

Journal: ACS medicinal chemistry letters

Published: December 12, 2025

Tumorigenic p53N236S balances aging and tumorigenesis via regulating DREAM/MMB and downstream telomere DNA replication pathways.

Tumorigenic p53N236S balances aging and tumorigenesis via regulating DREAM/MMB and downstream telomere DNA replication pathways.

Journal: Journal of molecular cell biology

Published: December 08, 2025

Development of an exon 27-skipping antisense oligonucleotide as a targeted therapy for refractory skin ulcers in Werner syndrome.

Development of an exon 27-skipping antisense oligonucleotide as a targeted therapy for refractory skin ulcers in Werner syndrome.

Journal: Molecular therapy. Nucleic acids

Published: October 21, 2025

Efficacy and safety of SGLT2 inhibitor on insulin resistance and hyperglycemia in Werner syndrome-A case report.

Efficacy and safety of SGLT2 inhibitor on insulin resistance and hyperglycemia in Werner syndrome-A case report.

Journal: Journal of diabetes investigation

Published: September 19, 2025

Editor's Note: Werner Syndrome Helicase Has a Critical Role in DNA Damage Responses in the Absence of a Functional Fanconi Anemia Pathway.

Editor's Note: Werner Syndrome Helicase Has a Critical Role in DNA Damage Responses in the Absence of a Functional Fanconi Anemia Pathway.

Journal: Cancer research

Published: August 06, 2025

Showing 1-12 of 1,710

Last Updated: 06/30/2026