Learn About Wolff-Parkinson-White Syndrome

What is the definition of Wolff-Parkinson-White Syndrome?

Wolff-Parkinson-White (WPW) syndrome is a condition in which there is an extra electrical pathway in the heart that leads to periods of rapid heart rate (tachycardia).

WPW syndrome is one of the most common causes of fast heart rate problems in infants and children.

What are the alternative names for Wolff-Parkinson-White Syndrome?

Preexcitation syndrome; WPW; Tachycardia - Wolff-Parkinson-White syndrome; Arrhythmia - WPW; Abnormal heart rhythm - WPW; Rapid heartbeat - WPW

What are the causes of Wolff-Parkinson-White Syndrome?

Normally, electrical signals follow a certain pathway through the heart. This helps the heart beat regularly. This prevents the heart from having extra beats or beats happening too soon.

In people with WPW syndrome, some of the heart's electrical signals go down an extra pathway. This may cause a very rapid heart rate called supraventricular tachycardia.

Most people with WPW syndrome do not have any other heart problems. However, this condition has been linked with other cardiac conditions, such as Ebstein anomaly. A form of the condition also runs in families.

What are the symptoms of Wolff-Parkinson-White Syndrome?

How often a rapid heart rate occurs varies depending on the person. Some people with WPW syndrome have only a few episodes of rapid heart rate. Others may have the rapid heart rate once or twice a week or more. Also, there may be no symptoms at all, so that condition is found when a heart test is done for another reason.

A person with this syndrome may have:

  • Chest pain or chest tightness
  • Dizziness
  • Lightheadedness
  • Fainting
  • Palpitations (a sensation of feeling your heart beating, usually quickly or irregularly)
  • Shortness of breath
Not sure about your diagnosis?
Check Your Symptoms
What are the current treatments for Wolff-Parkinson-White Syndrome?

Medicines, particularly antiarrhythmic drugs such as procainamide or amiodarone, may be used to control or prevent a rapid heartbeat.

If the heart rate does not return to normal with medical treatment, health care providers may use a type of therapy called electrical cardioversion (shock).

The long-term treatment for WPW syndrome is very often catheter ablation. This procedure involves inserting a tube (catheter) into a vein through a small cut near the groin up to the heart area. When the tip reaches the heart, the small area that is causing the fast heart rate is destroyed using a special type of energy called radiofrequency or by freezing it (cryoablation). This is done as part of an electrophysiologic study (EPS).

Before ablation is considered, you may be asked to undergo an exercise stress test to help decide if you need ablation.

Open heart surgery to burn or freeze the extra pathway may also provide a permanent cure for WPW syndrome. In most cases, this procedure is done only if you need heart surgery for other reasons.

Who are the top Wolff-Parkinson-White Syndrome Local Doctors?
Peter Aziz
Elite in Wolff-Parkinson-White Syndrome
Pediatrics
Elite in Wolff-Parkinson-White Syndrome
Pediatrics

Cleveland Clinic Children's Outpatient Center

8950 Euclid Avenue, 
Cleveland, OH 
Experience:
25+ years
Languages Spoken:
English

Peter Aziz is a Pediatrics provider in Cleveland, Ohio. Dr. Aziz has been practicing medicine for over 25 years and is rated as an Elite provider by MediFind in the treatment of Wolff-Parkinson-White Syndrome. His top areas of expertise are Wolff-Parkinson-White Syndrome, Long QT Syndrome, Double Discordia, Congenital Heart Disease (CHD), and Cardiac Ablation.

Andrew D. Blaufox
Elite in Wolff-Parkinson-White Syndrome
Pediatric Cardiology
Elite in Wolff-Parkinson-White Syndrome
Pediatric Cardiology

Cohen Children's Northwell Health Physician Partners Pediatric Specialists At Lake Success, 1111 Marcus Avenue

1111 MARCUS AVE, Entrance 4B, Suite M15, 
New Hyde Park, NY 
Languages Spoken:
English

My clinical and research areas of interest are: the management of arrhythmias in children and in adults with congenital heart disease including medical management, Cardiac Arrhythmia Ablation, as well as Pacemakers and ICDs. I also manage patients with Inherited Arrhythmias and those at risk for Sudden Cardiac Death. Dr. Blaufox is rated as an Elite provider by MediFind in the treatment of Wolff-Parkinson-White Syndrome. His top areas of expertise are Wolff-Parkinson-White Syndrome, Arrhythmias, Fainting, Myocarditis, and Cardiac Ablation.

 
 
 
 
Learn about our expert tiers
Learn More
Elite in Wolff-Parkinson-White Syndrome
Pediatric Cardiology | Pediatrics | Cardiac Electrophysiology
Elite in Wolff-Parkinson-White Syndrome
Pediatric Cardiology | Pediatrics | Cardiac Electrophysiology

Lpch Medical Group Div Of Lucile

725 Welch Rd, 
Palo Alto, CA 
Languages Spoken:
English

Scott Ceresnak is a Pediatric Cardiologist and a Pediatrics provider in Palo Alto, California. Dr. Ceresnak is rated as an Elite provider by MediFind in the treatment of Wolff-Parkinson-White Syndrome. His top areas of expertise are Wolff-Parkinson-White Syndrome, Congenital Heart Disease (CHD), Tetralogy of Fallot, Cardiac Ablation, and Heart Transplant.

What is the outlook (prognosis) for Wolff-Parkinson-White Syndrome?

Catheter ablation cures this disorder in most people. The success rate for the procedure ranges between 85% to 95%. Success rates will vary depending on the location and number of extra pathways.

What are the possible complications of Wolff-Parkinson-White Syndrome?

Complications may include:

  • Complications of surgery
  • Heart failure
  • Reduced blood pressure (caused by rapid heart rate)
  • Side effects of medicines

The most severe form of a rapid heartbeat is ventricular fibrillation (VF), which will rapidly lead to shock or death unless it is corrected. It can sometimes occur in people with WPW, particularly if they also have atrial fibrillation (AF), which is another type of abnormal heart rhythm. This type of rapid heartbeat requires emergency treatment and a procedure called cardioversion.

When should I contact a medical professional for Wolff-Parkinson-White Syndrome?

Contact your provider if:

  • You have symptoms of WPW syndrome.
  • You have this disorder and symptoms get worse or do not improve with treatment.

Talk to your provider about whether your family members should be screened for inherited forms of this condition.

What are the latest Wolff-Parkinson-White Syndrome Clinical Trials?
Discrimination of Right Versus Left Septal Accessory Pathway Before and During the Electrophysiological Study

Summary: Study of ECG and electrophysiological criteria which discriminate right versus left septal AP (both posteroseptal and anteroseptal AP). Both manifest and concealed APs will be considered .

Match to trials
Find the right clinical trials for you in under a minute
Get started
Clinical Profile and Current Strategies in Management of Wolf-Parkinson-White Syndrome and Asymptomatic Pre-excitation in Africa (a Multicenter WPW African Registry)

Summary: The purpose of this prospective observational study is to characterize the clinical profile of patients with WPW syndrome and patients with asymptomatic WPW pattern on ECG in different African countries and how these patients are managed across Africa Participants would include many different ethnicities at centers where the number of cardiac patients treated is high. All patients attending outpat...

Who are the sources who wrote this article ?

Published Date: February 27, 2024
Published By: Thomas S. Metkus, MD, Assistant Professor of Medicine and Surgery, Johns Hopkins University School of Medicine, Baltimore, MD. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Dalal AS, Van Hare GF. Disturbances of rate and rhythm of the heart. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 462.

Kalman JM, Sanders P. Supraventricular Tachycardias. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 65.

Zimetbaum P, Goldman L. Supraventricular ectopy and tachyarrhythmias. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 52.