Learn About X-Linked Ichthyosis

What is the definition of X-Linked Ichthyosis?
X-linked ichthyosis is a disorder in which the skin cells are produced at a normal rate but they do not separate properly at the surface of the stratum corneum (the outermost layer of the skin). This slows the rate of shedding of the skin cells, resulting in a build-up of scales. The scales of X-linked ichthyosis are often dark and usually cover only a portion of the body. Typically, the trunk and back of the neck are more likely to be affected. Scales are usually not found on the face, scalp, palms of the hands, and soles of the feet. X-linked ichthyosis mostly affects males. It is usually caused by a genetic change or deletion in the STS gene and is inherited in an X-linked recessive manner. In rare cases, the ichthyosis can be part of a genetic syndrome in which other parts of the body are affected.
Save information for later
Sign Up
What are the alternative names for X-Linked Ichthyosis?
  • X-linked ichthyosis
  • Placental steroid sulfatase deficiency
  • SSD
  • SSDD
  • Steroid sulfatase deficiency
  • Steroid sulfatase deficiency disease
  • X linked ichthyosis
Who are the top X-Linked Ichthyosis Local Doctors?
Learn about our expert tiers
Learn more
What are the latest X-Linked Ichthyosis Clinical Trials?
Match to trials
Find the right clinical trials for you in under a minute
Get started
Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for X-Linked Ichthyosis?