X-Linked Ichthyosis Symptoms, Doctors, Treatments, Advances & More

Learn About X-Linked Ichthyosis

What is the definition of X-Linked Ichthyosis?

X-linked ichthyosis is a disorder in which the skin cells are produced at a normal rate but they do not separate properly at the surface of the stratum corneum (the outermost layer of the skin). This slows the rate of shedding of the skin cells, resulting in a build-up of scales. The scales of X-linked ichthyosis are often dark and usually cover only a portion of the body. Typically, the trunk and back of the neck are more likely to be affected. Scales are usually not found on the face, scalp, palms of the hands, and soles of the feet. X-linked ichthyosis mostly affects males. It is usually caused by a genetic change or deletion in the STS gene and is inherited in an X-linked recessive manner. In rare cases, the ichthyosis can be part of a genetic syndrome in which other parts of the body are affected.

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What are the alternative names for X-Linked Ichthyosis?

X-linked ichthyosis
Placental steroid sulfatase deficiency
SSD
SSDD
Steroid sulfatase deficiency
Steroid sulfatase deficiency disease
X linked ichthyosis

Who are the top X-Linked Ichthyosis Local Doctors?

Timothy G. Barrett

Elite

Highly rated in

conditions

Birmingham Women's And Children's Hospital

Birmingham, GB

Timothy Barrett practices in Birmingham, United Kingdom. Barrett is rated as an Elite expert by MediFind in the treatment of X-Linked Ichthyosis. He is also highly rated in 16 other conditions, according to our data. His top areas of expertise are Wolfram Syndrome, X-Linked Ichthyosis, Diabetes Insipidus (DI), and Ovarian Overproduction of Androgens.

Renuka P. Dias

Elite

Highly rated in

conditions

University Of Birmingham

Birmingham, ENG, GB

Renuka Dias practices in Birmingham, United Kingdom. Dias is rated as an Elite expert by MediFind in the treatment of X-Linked Ichthyosis. She is also highly rated in 9 other conditions, according to our data. Her top areas of expertise are X-Linked Ichthyosis, Ovarian Overproduction of Androgens, Russell-Silver Dwarfism, and Wolfram Syndrome.

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Alberto Guijo-Sanchez

Elite

Highly rated in

conditions

Division Of Pediatric Endocrinology And Diabetology

Steroid Research And Mass Spectrometry Unit, University Children's Hospital,

Giessen, HE, DE

Alberto Guijo-Sanchez practices in Giessen, Germany. Guijo-Sanchez is rated as an Elite expert by MediFind in the treatment of X-Linked Ichthyosis. He is also highly rated in 1 other condition, according to our data. His top areas of expertise are X-Linked Ichthyosis, Apparent Mineralocorticoid Excess, Intraductal Papilloma, and Cushing Syndrome.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for X-Linked Ichthyosis?

Steroid sulfatase deficiency causes cellular senescence and abnormal differentiation by inducing Yippee-like 3 expression in human keratinocytes.