Xanthoma Overview
Learn About Xanthoma
Xanthoma is a skin condition in which certain fats build up under the surface of the skin.
Skin growths - fatty; Xanthelasma
Xanthomas are common, especially among older adults and people with high blood lipids (fats). Xanthomas vary in size. Some are very small. Others are bigger than 3 inches (7.5 centimeters) in diameter. They may appear anywhere on the body. But, they are most often seen on the elbows, joints, tendons, knees, hands, feet, or buttocks.
Xanthomas may be a sign of a medical condition that involves an increase in blood lipids. Such conditions include:
- Certain cancers
- Diabetes
- High blood cholesterol levels
- Inherited metabolic disorders, such as familial hypercholesterolemia
- Scarring of the liver due to blocked bile ducts (primary biliary cirrhosis)
- Inflammation and swelling of the pancreas (pancreatitis)
- Underactive thyroid (hypothyroidism)
Xanthelasma palpebra is a common type of xanthoma that appears on the eyelids. It usually occurs without any underlying medical condition.
A xanthoma looks like a yellow to orange bump (papule) with defined borders. There may be several individual ones or they may form clusters.
If you have a disease that causes increased blood lipids, treating the condition may help reduce the development of xanthomas.
If the growth bothers you, your provider may remove it by surgery or with a laser. However, xanthomas may come back after surgery.
Bon Secours Charity Health System Medical Group, P.C.
Scott Bernstein is an Internal Medicine provider in Pomona, New York. Dr. Bernstein and is rated as an Advanced provider by MediFind in the treatment of Xanthoma. His top areas of expertise are Sitosterolemia, High Cholesterol, Pleurisy, Gastrostomy, and Hip Replacement.
Crystal Run Healthcare Physicians Llp
Gregory Spencer is an Internal Medicine provider in West Nyack, New York. Dr. Spencer and is rated as an Experienced provider by MediFind in the treatment of Xanthoma. His top areas of expertise are Cellulitis, Polycythemia Vera, Peptic Ulcer, and Candida Infection of the Skin.
Rockland Ny Medical Services, P.C.
Yanina Kotlyar is an Internal Medicine provider in New City, New York. Dr. Kotlyar and is rated as an Experienced provider by MediFind in the treatment of Xanthoma. Her top areas of expertise are Vasoconstriction, Lyme Disease, Complex Regional Pain Syndrome, and Inappropriate Sinus Tachycardia (IST).
The growth is noncancerous and painless, but it may be a sign of another medical condition.
Call your provider if xanthomas develop. They may indicate an underlying disorder that needs treatment.
To reduce the development of xanthomas, you may need to control your blood triglyceride and cholesterol levels.
Summary: This study will evaluate people with dyslipidemias - disorders that affect the fat content in the blood. Fats, or lipids, such as cholesterol and triglycerides, are carried in the blood in particles called lipoproteins. These particles are involved in causing blood vessel diseases that can lead to conditions like atherosclerosis (hardening of the arteries) or heart attack. Participants will underg...
Summary: The rare histiocytic disorders (RHDs) are characterized by the infiltration of one or more organs by non-LCH histiocytes. They can range from localized disease that resolves spontaneously, to progressive disseminated forms that can be sometimes life-threatening. Since they are extremely rare, there is limited understanding of their causes and best treatment options. Physicians, patients and parent...
Published Date: May 31, 2023
Published By: Ramin Fathi, MD, FAAD, Director, Phoenix Surgical Dermatology Group, Phoenix, AZ. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Dinulos JGH. Cutaneous manifestations of internal disease. In: Dinulos JGH, ed. Habif's Clinical Dermatology. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 26.
Massengale WT. Xanthomas. In: Bolognia JL, Schaffer JV, Cerroni L, eds. Dermatology. 4th ed. Philadelphia, PA: Elsevier; 2018:chap 92.
White LE, Horenstein MG, Shea CR. Xanthomas. In: Lebwohl MG, Heymann WR, Coulson IH, Murrell DF, eds. Treatment of Skin Disease: Comprehensive Therapeutic Strategies. 6th ed. Philadelphia, PA: Elsevier; 2022:chap 256.