Learn About Y Chromosome Infertility
Y chromosome infertility is a condition that affects the production of sperm and causes male infertility, which means it is difficult or impossible for affected men to father children. An affected man's body may produce no mature sperm cells (azoospermia), fewer than the usual number of sperm cells (oligospermia), or sperm cells that are abnormally shaped or that do not move properly. Men with Y chromosome infertility do not have any other signs or symptoms related to the condition.
As its name suggests, this form of infertility is caused by changes in the Y chromosome. People normally have 46 chromosomes in each cell. Two of the 46 chromosomes are sex chromosomes, called X and Y. Females have two X chromosomes (46,XX), and males have one X chromosome and one Y chromosome (46,XY).
Y chromosome infertility occurs in approximately 1 in 2,000 to 1 in 3,000 males of all ethnic groups. This condition accounts for about 13 percent of cases of azoospermia and 5 percent of severe oligospermia.
Because Y chromosome infertility impedes the ability to father children, this condition is usually not inherited. Most cases of this condition result from new (de novo) deletions on the Y chromosome that occur during formation of sperm cells in an affected individual's father who is not himself infertile. These cases occur in men with no history of the disorder in their family.
Csilla Krausz practices in Florence, Italy. Ms. Krausz is rated as an Elite expert by MediFind in the treatment of Y Chromosome Infertility. Her top areas of expertise are Partial Deletion of Y, Y Chromosome Infertility, Testicular Failure, Hormone Replacement Therapy (HRT), and Vasectomy.
Shady Grove Fertility - Raleigh
Leah Bressler, M.D., M.P.H., is board certified in obstetrics and gynecology (OB/GYN) as well as reproductive endocrinology and infertility (REI). She grew up in Clinton, North Carolina and attended UNC Chapel Hill as a Morehead scholar. Dr. Bressler earned her medical degree from Harvard Medical School while also completing her Master’s in Public Health. She then completed her residency in OB/GYN at Northwestern University Feinberg School of Medicine and Cook County Hospitals in Chicago, Illinois. From there, Dr. Bressler completed her REI fellowship at the University of North Carolina at Chapel Hill. Prior to joining SGF, Dr. Bressler served as the Medical Director, Director of Third-Party Reproduction, Associate Fellowship Program Director, and Residency Rotation Director at UNC. As an avid researcher, she has first-author publications in the top REI journals such as Human Reproduction, Fertility & Sterility, Obstetrics & Gynecology, and the American Journal of Obstetrics & Gynecology. Dr. Bressler is a member of several professional organizations, including the American Society for Reproductive Medicine (ASRM), the American College of Obstetricians and Gynecologists (ACOG). Dr. Bressler provides patient care at SGF’s Raleigh, North Carolina, location. In her spare time, she enjoys playing golf with her partner and friends, watching her kids play sports, running, and baking. . Her top areas of expertise are Infertility, Polycystic Ovary Syndrome, Sertoli Cell-Only Syndrome, and Tubal Disease.
Leilei Li practices in Changchun, China. Li is rated as a Distinguished expert by MediFind in the treatment of Y Chromosome Infertility. Their top areas of expertise are Y Chromosome Infertility, Partial Deletion of Y, Intersex, and Mosaic Trisomy 9.
Published Date: January 01, 2019
Published By: National Institutes of Health