Safinamide

Last Updated: 11/08/2026

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Found 359 publications

NaV1.7-dependent peripheral sensitization drives chronic pain in Parkinson's disease.

NaV1.7-dependent peripheral sensitization drives chronic pain in Parkinson's disease.

Journal: bioRxiv : the preprint server for biology

Published: September 24, 2026

Neuroprotective potential of safinamide against LPS-induced neuroinflammation and cognitive dysfunction in mice.

Neuroprotective potential of safinamide against LPS-induced neuroinflammation and cognitive dysfunction in mice.

Journal: Neuroscience letters

Published: August 18, 2026

Daturaolone from Datura metel L. Inhibits acetylcholinesterase and monoamine oxidase B.

Daturaolone from Datura metel L. Inhibits acetylcholinesterase and monoamine oxidase B.

Journal: Natural product research

Published: August 05, 2026

Efficacy and Safety of Safinamide as an Adjunct to Levodopa for Motor Fluctuations in Parkinson's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Efficacy and Safety of Safinamide as an Adjunct to Levodopa for Motor Fluctuations in Parkinson's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Journal: Parkinson's disease

Published: June 03, 2026

Ekbom Spectrum Psychosis Associated with 24-hour Continuous Subcutaneous Foslevodopa/Foscarbidopa Infusion in Parkinson's Disease.

Ekbom Spectrum Psychosis Associated with 24-hour Continuous Subcutaneous Foslevodopa/Foscarbidopa Infusion in Parkinson's Disease.

Journal: Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

Published: May 11, 2026

Marked Improvement of Sialorrhea with Safinamide in Parkinson's Disease: A Case Series.

Marked Improvement of Sialorrhea with Safinamide in Parkinson's Disease: A Case Series.

Journal: Movement disorders : official journal of the Movement Disorder Society

Published: April 24, 2026

Safinamide dual molecular mechanisms: sodium channel and glutamate modulation as a translational rationale for neuropathic pain - A narrative review.

Safinamide dual molecular mechanisms: sodium channel and glutamate modulation as a translational rationale for neuropathic pain - A narrative review.

Journal: Drug metabolism and personalized therapy

Published: April 23, 2026

Design, synthesis and in silico evaluation of quinoline-indole chalcone hybrids for potential antibacterial, anticancer and antineurodegenerative applications.

Design, synthesis and in silico evaluation of quinoline-indole chalcone hybrids for potential antibacterial, anticancer and antineurodegenerative applications.

Journal: In silico pharmacology

Published: April 21, 2026

Add-on safinamide and amantadine in Filipino Parkinson's disease patients with motor fluctuations: a retrospective exploratory cohort study.

Add-on safinamide and amantadine in Filipino Parkinson's disease patients with motor fluctuations: a retrospective exploratory cohort study.

Journal: Journal of neural transmission (Vienna, Austria : 1996)

Published: April 08, 2026

Pharmacological treatments of REM sleep behaviour disorder in synucleinopathies: a systematic review of effectiveness and safety.

Pharmacological treatments of REM sleep behaviour disorder in synucleinopathies: a systematic review of effectiveness and safety.

Journal: Sleep medicine

Published: April 08, 2026

Application of In Silico QSAR and Molecular Docking Studies to a Series of Xanthine-Based Analogues and Design, Synthesis and Pharmacological Evaluation of Identified New Potential Selective MAO-B Inhibitors.

Application of In Silico QSAR and Molecular Docking Studies to a Series of Xanthine-Based Analogues and Design, Synthesis and Pharmacological Evaluation of Identified New Potential Selective MAO-B Inhibitors.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: April 06, 2026

Combination therapy of levodopa with safinamide is more effective than with rasagiline and zonisamide in Asian Parkinson's disease patients with motor fluctuations: a systematic review and network meta-analysis of randomized controlled trials.

Combination therapy of levodopa with safinamide is more effective than with rasagiline and zonisamide in Asian Parkinson's disease patients with motor fluctuations: a systematic review and network meta-analysis of randomized controlled trials.

Journal: Journal of neurology

Published: March 23, 2026

Showing 1-12 of 359

Last Updated: 11/08/2026