Istradefylline
Last Updated: 11/08/2026
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Found 301 publications
Striatofugal balance and beneficial effects of facilitating nucleus accumbens mGlu4 receptor activity in the Fmr1-/- mouse model of Fragile X Syndrome.
Journal: Pharmacological research
Published: July 16, 2026
Design, Synthesis, and Anti-Inflammatory Activity Evaluation of Novel thieno[2,3-d]Pyrimidin-4(3H)-One-Based NLRP3 Inflammasome Inhibitors.
Journal: Journal of medicinal chemistry
Published: July 07, 2026
Changes in sleep disturbances and quality of life associated with Istradefylline in patients with Parkinson's disease: an exploratory polysomnographic study.
Journal: Clinical parkinsonism & related disorders
Published: June 24, 2026
Intraperitoneal Administration of Adenosine A2A Receptor Antagonist Reduces Neuroinflammatory and Antioxidant Responses in GM2 Gangliosidosis Mouse Model.
Journal: Neuropharmacology
Published: June 18, 2026
Electronic structure-activity relationships of adenine-based istradefylline derivatives investigated by DFT, topological analysis, and exploratory neuronal excitability modeling.
Journal: Scientific reports
Published: April 17, 2026
Adenosine A2A receptors in the chorioid plexus are causal in mediating the development of hydrocephalus.
Journal: Purinergic signalling
Published: March 15, 2026
Early neural shift detection using functional magnetic resonance imaging: a pilot study with Parkinson's disease patients undergoing istradefylline and hybrid assistive limb interventions.
Journal: Frontiers in neurology
Published: February 24, 2026
Expanding Clinical Experience With Istradefylline in ADCY5-Related Movement Disorder: A Case With No Benefit.
Journal: Movement disorders clinical practice
Published: February 02, 2026
Purinergic modulation in Parkinson's disease: the dual role of istradefylline in motor and cognitive outcomes.
Journal: Purinergic signalling
Published: February 02, 2026
Dual CD73/A2AR blockade modulates the neurotoxic astrocyte phenotype without disrupting core inflammatory signaling.
Journal: Frontiers in pharmacology
Published: December 30, 2025
Caffeine Mitigates Adenosine-Mediated Angiogenic Properties of Choroidal Endothelial Cells Through Antagonism of A1 Adenosine Receptor and PI3K-AKT Axis.
Journal: Cells
Published: December 10, 2025
High-throughput screening for the discovery of antidepressants targeting adenosine A2A receptors.
Journal: Bioorganic chemistry
Published: November 26, 2025
Last Updated: 11/08/2026