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Last Updated: 10/31/2025

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Found 1149 publications

New regimens of benznidazole for the treatment of chronic Chagas disease in adult participants in indeterminate form or with mild cardiac progression (NuestroBen study): protocol for a phase III randomised, multicentre non-inferiority clinical trial.

New regimens of benznidazole for the treatment of chronic Chagas disease in adult participants in indeterminate form or with mild cardiac progression (NuestroBen study): protocol for a phase III randomised, multicentre non-inferiority clinical trial.

Journal: BMJ open
Published: September 30, 2025

Engineering a nifurtimox nanosuspension: toward improved pharmaceutical attributes.

Engineering a nifurtimox nanosuspension: toward improved pharmaceutical attributes.

Journal: Drug delivery and translational research
Published: July 28, 2025

Human African Trypanosomiasis (HAT): Epidemiology, Biological Diagnosis and Treatment: A Review.

Human African Trypanosomiasis (HAT): Epidemiology, Biological Diagnosis and Treatment: A Review.

Journal: Acta parasitologica
Published: June 28, 2025

Enantioselective Properties of Neglected Drug Nifurtimox on Polysaccharide and Macrocyclic Glycopeptide Chiral Stationary Phases by Green HPLC Separation Methods.

Enantioselective Properties of Neglected Drug Nifurtimox on Polysaccharide and Macrocyclic Glycopeptide Chiral Stationary Phases by Green HPLC Separation Methods.

Journal: Journal of separation science
Published: June 27, 2025

Trypanosoma cruzi Growth Is Impaired by Oleoresin and Leaf Hydroalcoholic Extract from Copaifera multijuga in Human Trophoblast and Placental Explants.

Trypanosoma cruzi Growth Is Impaired by Oleoresin and Leaf Hydroalcoholic Extract from Copaifera multijuga in Human Trophoblast and Placental Explants.

Journal: Pathogens (Basel, Switzerland)
Published: June 16, 2025

Buddleja globosa Leaf Methanolic Extract Acts Against Trypanosoma cruzi Parasites by Inducing Mitochondrial Inner Membrane Hyperpolarization.

Buddleja globosa Leaf Methanolic Extract Acts Against Trypanosoma cruzi Parasites by Inducing Mitochondrial Inner Membrane Hyperpolarization.

Journal: Plants (Basel, Switzerland)
Published: June 09, 2025

Inhibitory Activity of Compounds Obtained from Streptomyces Against Trypanosoma cruzi.

Inhibitory Activity of Compounds Obtained from Streptomyces Against Trypanosoma cruzi.

Journal: Pathogens (Basel, Switzerland)
Published: May 22, 2025

Cutaneous reactions during treatment with Nifurtimox or Benznidazole among Trypanosoma cruzi seropositive adults without symptomatic cardiomyopathy: A safety sub analysis of a placebo-controlled randomised trial.

Cutaneous reactions during treatment with Nifurtimox or Benznidazole among Trypanosoma cruzi seropositive adults without symptomatic cardiomyopathy: A safety sub analysis of a placebo-controlled randomised trial.

Journal: Tropical medicine & international health : TM & IH
Published: May 19, 2025

Mechanistic, in-silico and in vitro studies with nitrofurans reveal potent leishmanicidal activity and inhibition of trypanothione reductase.

Mechanistic, in-silico and in vitro studies with nitrofurans reveal potent leishmanicidal activity and inhibition of trypanothione reductase.

Journal: International journal for parasitology. Drugs and drug resistance
Published: May 05, 2025

Pharmacokinetics of Racemic Eflornithine in Human Plasma and Cerebrospinal Fluid: Clinical Perspectives for L-eflornithine Against Human African Trypanosomiasis.

Pharmacokinetics of Racemic Eflornithine in Human Plasma and Cerebrospinal Fluid: Clinical Perspectives for L-eflornithine Against Human African Trypanosomiasis.

Journal: The AAPS journal
Published: May 05, 2025

Use of fexinidazole in gambiense human African trypanosomiasis: a retrospective analysis of cases treated in Lui Hospital, South Sudan (2018-2024).

Use of fexinidazole in gambiense human African trypanosomiasis: a retrospective analysis of cases treated in Lui Hospital, South Sudan (2018-2024).

Journal: Infection
Published: April 15, 2025

Antitrypanosomal therapy for Chagas disease: A single center experience with adverse drug reactions and strategies for enhancing treatment completion.

Antitrypanosomal therapy for Chagas disease: A single center experience with adverse drug reactions and strategies for enhancing treatment completion.

Journal: PLoS neglected tropical diseases
Published: April 07, 2025
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Last Updated: 10/31/2025