Nifurtimox

Last Updated: 09/26/2026

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Found 1201 publications

A multicentre randomised, double-blind, double-dummy phase II clinical trial of benznidazole versus nifurtimox in adults with chronic Chagas disease in Brazil, alongside a prospective cohort: the BENBRASIL trial protocol.

A multicentre randomised, double-blind, double-dummy phase II clinical trial of benznidazole versus nifurtimox in adults with chronic Chagas disease in Brazil, alongside a prospective cohort: the BENBRASIL trial protocol.

Journal: BMJ open

Published: July 17, 2026

Consensus framework for developing a target product profile of real-time PCR in Chagas disease therapeutic monitoring.

Consensus framework for developing a target product profile of real-time PCR in Chagas disease therapeutic monitoring.

Journal: PLoS neglected tropical diseases

Published: July 09, 2026

Phenotypic Analysis of the Anti-T. cruzi Activity of Natural Products Obtained from Brazilian Botanical Sources.

Phenotypic Analysis of the Anti-T. cruzi Activity of Natural Products Obtained from Brazilian Botanical Sources.

Journal: Molecules (Basel, Switzerland)

Published: July 01, 2026

Chagas disease: An increasing clinical concern.

Chagas disease: An increasing clinical concern.

Journal: Nursing

Published: June 16, 2026

Human Histatin 5 Exerts Anti-Trypanosomal Activity Against Trypanosoma cruzi and Induces Ultrastructural Damage, Apoptosis-like Cell Death, and Oxidative/Nitrosative Stress.

Human Histatin 5 Exerts Anti-Trypanosomal Activity Against Trypanosoma cruzi and Induces Ultrastructural Damage, Apoptosis-like Cell Death, and Oxidative/Nitrosative Stress.

Journal: International journal of molecular sciences

Published: June 03, 2026

[Lys3, Lys4] M-PONTX-Dq3a [1-15]: a selective dinoponeratoxin-derived peptide that disrupts parasite membranes and inhibits TcGAPDH activity in Trypanosoma cruzi.

[Lys3, Lys4] M-PONTX-Dq3a [1-15]: a selective dinoponeratoxin-derived peptide that disrupts parasite membranes and inhibits TcGAPDH activity in Trypanosoma cruzi.

Journal: Toxicon : official journal of the International Society on Toxinology

Published: May 22, 2026

Cafestol and kahweol: coffee diterpenes with trypanocidal activity and cardioprotective effects.

Cafestol and kahweol: coffee diterpenes with trypanocidal activity and cardioprotective effects.

Journal: Frontiers in cellular and infection microbiology

Published: May 19, 2026

Chemical synthesis and biological activity of semisynthetic derivatives against Chagas disease and leishmaniasis composed of fragments of natural products and 1,2,3-triazine 1-oxide scaffold.

Chemical synthesis and biological activity of semisynthetic derivatives against Chagas disease and leishmaniasis composed of fragments of natural products and 1,2,3-triazine 1-oxide scaffold.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: May 19, 2026

Trypanosoma cruzi Retinitis Following Donor-Derived Chagas Disease After Heart Transplantation.

Trypanosoma cruzi Retinitis Following Donor-Derived Chagas Disease After Heart Transplantation.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Published: May 06, 2026

Purine derivatives as potential agents against Chagas disease: Ex vivo, in vitro, in silico evaluation, and identification of targets in Trypanosoma cruzi.

Purine derivatives as potential agents against Chagas disease: Ex vivo, in vitro, in silico evaluation, and identification of targets in Trypanosoma cruzi.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: April 20, 2026

5‑Nitrofuran-Semicarbazone Hybrids as Antitrypanosomal Agents: Structure-Activity Relationship and Nitroreductase Activation.

5‑Nitrofuran-Semicarbazone Hybrids as Antitrypanosomal Agents: Structure-Activity Relationship and Nitroreductase Activation.

Journal: ACS medicinal chemistry letters

Published: April 13, 2026

In Vivo Trypanocidal Activity of the Drug Disulfiram Combined with Benznidazole.

In Vivo Trypanocidal Activity of the Drug Disulfiram Combined with Benznidazole.

Journal: ACS infectious diseases

Published: March 31, 2026

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Last Updated: 09/26/2026