Comparation of Endoscopic Biopsy and Postoperative Specimen for the Molecular Diagnosis of Gastric Cancer
Status: Recruiting
Location: See location...
Intervention Type: Device, Procedure
Study Type: Observational
SUMMARY
This study aims to test the hypothesis that the diagnosis for histological type, histological grade, LAUREN type, HER-2 expression, MSI/dMMR status, and EBV status in gastric cancer is at least as reliable when performed on endoscopic biopsy specimens as on surgical resection specimens.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
View:
• Lower age limit of research subjects 18 years old and upper age limit of 75 years old.
• Histologically proven primary gastric adenocarcinoma (Diagnostic biopsies must be collected within 12 months prior to enrollment).
• Written informed consent from the patient.
• Patients planned for radical R0 gastrectomy.
Locations
Other Locations
China
Fudan University Shanghai Cancer Center
RECRUITING
Shanghai
Contact Information
Primary
Dazhi Xu, PHD, MD
xudzh@shca.org.cn
(+86) 021-38196215
Time Frame
Start Date: 2021-05-24
Estimated Completion Date: 2026-09-01
Participants
Target number of participants: 510
Treatments
the pathology of endoscopic biopsy
The histological type, histological grade, LAUREN type, HER-2 expression, MSI/dMMR status, and EBV status of gastric cancer testing on endoscopic biopsies
the pathology of surgical resection specimen
The histological type, histological grade, LAUREN type, HER-2 expression, MSI/dMMR status, and EBV status of gastric cancer testing on surgical resection specimens
Related Therapeutic Areas
Sponsors
Leads: Fudan University