The Prognostic Performance of Liquid Biopsy in Peritoneal Lavage and Plasma of Patients With Locally Advanced Gastric Cancer (LIQUID Study)

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This study investigates the prognostic role of liquid biopsy in patients with locally advanced gastric cancer. Liquid biopsy for the detection of circulating tumor DNA will be performed: * In the peritoneal lavage, during staging laparoscopy (if indicated) and during curative gastrectomy * In plasma, before staging laparoscopy (if indicated), before curative gastrectomy, at hospital discharge, three months after surgery/at the end of adjuvant therapy, and in case of disease recurrence. The aim of this study is to determine the predictive power of liquid biopsy on overall survival and disease free survival.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Histologically proven gastric or gastro-esophageal junction (GEJ -Siewert type II -III) adenocarcinoma

• More than cT2 and/or N + (UICC 8th edition)

• Written informed consent

Locations
Other Locations
Italy
Fondazione IRCSS Istituto Nazionale dei Tumori
RECRUITING
Milan
Contact Information
Primary
Carlo Sposito, MD
carlo.sposito@istitutotumori.it
02-2390-3496
Time Frame
Start Date: 2020-05-08
Estimated Completion Date: 2025-05
Participants
Target number of participants: 150
Related Therapeutic Areas
Sponsors
Leads: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

This content was sourced from clinicaltrials.gov