Prospective Randomized Controlled Trial of Ropivacaine-Poloxamer 407 Based Gel Application on Postoperative Pain After Open Gastrectomy
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The study evaluates the efficacy of Ropivacaine-Poloxamer 407 hydrogel in reducing postoperative pain following open gastrectomy.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Healthy Volunteers: f
View:
• Patients with a histologically confirmed diagnosis of gastric adenocarcinoma prior to surgery.
• Patients who have undergone a complete surgical resection (R0 resection).
• Patients with an ASA (American Society of Anesthesiologists) score of 3 or below.
• Patients aged 20 years or older.
Locations
Other Locations
Republic of Korea
GangnamSeverance Hospital
RECRUITING
Seoul
Contact Information
Primary
Shiyeol Jun
gsirb@yuhs.ac
82-2-2019-4601
Time Frame
Start Date: 2025-01-30
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 48
Treatments
Experimental: Peritoneal application group
Patients who applied Ropivacaine-Poloxamer 407 hydrogel on space between peritoneum and fascia
Experimental: Subcutaneous injection group
Patients who injected Ropivacaine-Poloxamer 407 hydrogel on subcutaneous area
Placebo_comparator: Placebo group
Patients who did not apply Ropivacaine-Poloxamer 407 hydrogel
Related Therapeutic Areas
Sponsors
Leads: Gangnam Severance Hospital