Pain and Clinical Reflections in Pelvic Congestion Syndrome,

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Pelvic congestion syndrome (PKS) occurs as a result of dysfunction of the veins in the pelvic area. It is currently called pelvic venous disease. This definition also includes some diseases of the pelvic region such as May-Thurner and Nutcracker syndrome. Dilatation and reflux are usually observed in the para-uterine or ovarian veins. PCS is one of the important causes of chronic pelvic pain (CPA). Pain in PCS is unrelated to the menstrual cycle. PCS is frequently seen in multiparous women in the reproductive period. Pregnancy worsens the clinical condition of patients with PCS due to mechanical pressure on the pelvic region vessels in pregnant women. Although the underlying cause of PCS is thought to be hormonal factors related to progesterone and estrogen, its etiology has not been fully elucidated and is thought to be multifactorial.GnRH analogues and medroxyprogesterone, which have side effects such as menstrual irregularity, osteoporosis and weight gain, were previously used in the medical treatment of PCS. Combined oral hormonal contraceptives, vasoactive flavonoid fraction drugs, nonsteroidal anti-inflammatory (NSAID) drugs for pain relief, Gabapentin, and Amiltriptyline are still used in the treatment of PCS. In the past, traditional hysterectomy and oophorectomy were performed surgically. Laparoscopic ovarian vein ligation has been performed since the early 2000s, but its popularity has decreased due to potential complications such as retroperitoneal hematoma, ureteral injury, and thrombosis. Endovascular intervention is more preferred today due to its low complications and high success in treatment.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 50
Healthy Volunteers: f
View:

• It is planned to include 54 female patients between the ages of 18-50,

• who have abdominopelvic pain for more than 6 months

• who have \>6 mm dilatation in the pelvic veins on transvaginal or transabdominal ultrasonography along with clinical, physical examination and symptoms.

Locations
Other Locations
Turkey
Kanuni Sultan Süleyman Training and Research Hospital
RECRUITING
Istanbul
Contact Information
Primary
halil ibrahim altun
halilibrahim_altun@yahoo.com
+905072774773
Time Frame
Start Date: 2024-06-10
Estimated Completion Date: 2024-09-30
Participants
Target number of participants: 54
Treatments
Pain and Clinical Reflections in Pelvic Congestion Syndrome
Sponsors
Leads: Kanuni Sultan Suleyman Training and Research Hospital

This content was sourced from clinicaltrials.gov