Ultrasound-Guided Erector Spinae Block Versus Serratus Anterior Block for Perioperative Analgesia In Patients Undergoing Modified Radical Mastectomy Surgery

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Modified radical mastectomy is one of the commonly performed breast surgery. Postoperative pain following mastectomy should be minimised, as in a number of women it may chronically persist for months in the form of postmastectomy pain syndrome. Morphine administration for acute pain after mastectomy surgery has many side effects. Regional block techniques as paravertebral block and thoracic epidural anathesia has possible complications and technical difficulties. The new alternative regional techniques such as erector spinae plane block and serratus anterior plane block are clinical trials for providing a safe, easy and painless anesthetic procedure with good hemodynamic and recovery profile with adequate perioperative analgesia for a large section of patients undergoing mastectomy operation in order to reduce opiods consumption and subsequently avoid opiod-related adverse effects.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 21
Maximum Age: 60
Healthy Volunteers: f
View:

• Written informed consent from the patient.

‣ Age: 21 - 60 years old.

⁃ Gender: female patients.

⁃ Body mass index: \< 35 kg/m2.

⁃ Physical status: ASA grade I-II (American society of anesthiologists).

⁃ Type of operation: unilateral modified radical mastectomy operation.

Locations
Other Locations
Egypt
Zagazig
RECRUITING
Zagazig
Contact Information
Primary
Asmaa M Galal Eldin, MD
asmaa.galal79@gmail.com
01200726092
Backup
sara H Yousif, master
Saraheikal10@gmail.com
01015051856
Time Frame
Start Date: 2024-05-10
Estimated Completion Date: 2024-08-01
Participants
Target number of participants: 75
Treatments
Active_comparator: Erector Spinae Plane Block
patient place in sitting position. Type of needle Using 22-gauge spinal needle 10 cm Linear ultrasound probe is placed in a longitudinal parasagittal orientation 3 cm lateral to the T5 spinous process.~The erector spinae muscle is identified superficial to the tip of The T5 transverse process.~Needle insertion The needle is inserted in- plane superior to inferior approach. The tip of the needle is placed into the fascial plane on the deep aspect of erector spinae muscle.~The location of the needle tip is confirmed by visible normal saline fluid spread separating erector spinae muscle off the bony shadow of the transverse process on ultrasonographic imaging .~Local anesthetic and volume Injection of 20 ml of bupivacaine 0.25 %.
Active_comparator: Serratus Anterior Plane Block:
The patient lies supine with placing the ipsi-lateral upper limb in abduction at 90° positio Using 22-gauge spinal needle 10 cm length. After skin sterilization, Ultrasound device with high frequency \[9-12\] and superficial linear probe that is first placed inferior to the middle of the clavicle and moved laterally and downward to locate the 1st rib where pectoralis major and pectoralis minor muscles are identified at this US window.~The US probe is moved toward axilla till serratus anterior muscle is identified above 2nd, 3rd and 4th ribs. The transducer is held at a slightly oblique angle at the level of the 4th and 5th rib, with the upper edge supero-anterior and the lower edge infero-anterior.~Needle insertion After infiltration of the skin at puncture site with 3 ml of lidocaine 1%, the needle is inserted inplane between the anterior serratus and the latissimus dorsi muscle on the mid-axillary line.~Injection of 20 mL of 0.25% bupivacaine.
Active_comparator: control group
patients will receive only general anesthesia for Modified Radical Mastectomy.
Related Therapeutic Areas
Sponsors
Leads: Zagazig University

This content was sourced from clinicaltrials.gov