A Prospective Multicenter Study of Transbronchial Microwave Ablation Using Robotic-Assisted Bronchoscopy in Subjects With Oligometastatic Tumors in the Lung

Status: Terminated
Location: See all (10) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This is a prospective, multicenter, single-arm study on transbronchial microwave ablation using the NEUWAVE FLEX Microwave Ablation System and Accessories on oligometastatic tumors in the peripheral lung, guided by the Auris MONARCH Platform for visualization and access while using cone beam CT (computed tomography) to confirm probe tip placement and final ablation zone. The primary endpoint is Technique Efficacy, assessed 30-days post-ablation via CT imaging.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 22
Healthy Volunteers: f
View:

• Signed informed consent.

• Subjects greater or equal to 22 years old.

• Performance status 0-2 (Eastern Cooperative Oncology Group classification (ECOG).

• Willing to fulfill all follow-up visit requirements.

• Subjects with at least one oligometastatic lung tumor where the primary tumor is controlled (in the opinion of the investigator or treating oncologist).

• Oligometastatic lung tumor(s) planned to be ablated in the outer two-thirds of the lung and not closer than 1cm to the pleura.

Locations
United States
California
Stanford University School of Medicine
Stanford
Connecticut
UCONN Health
Farmington
Minnesota
Minnesota Lung Center
Minneapolis
North Carolina
FirstHealth Moore Regional Hospital
Pinehurst
Ohio
Cleveland Clinic
Cleveland
Pennsylvania
University of Pennsylvania
Philadelphia
Texas
MD Anderson
Houston
Other Locations
Canada
Centre Hospitalier de l'Universite de Montreal
Montreal
University of Toronto
Toronto
Hong Kong Special Administrative Region
Prince of Wales Hospital
Shatin
Time Frame
Start Date: 2022-10-21
Completion Date: 2024-10-18
Participants
Target number of participants: 12
Treatments
Experimental: Transbronchial Microwave Ablation
Transbronchial microwave ablation will be performed using the NEUWAVE FLEX Microwave Ablation System and Accessories on oligometastatic tumors in the peripheral lung, guided by the Auris MONARCH Platform for visualization and access while using cone beam CT (computed tomography) to confirm probe tip placement and final ablation zone.
Sponsors
Leads: Ethicon, Inc.

This content was sourced from clinicaltrials.gov

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