Angioplasty Clinical Trials

Clinical trials related to Angioplasty Procedure

Transulnar Access in Patients With Ipsilateral Radial Artery Occlusion Undergoing Coronary Angiography or Angioplasty: Safety and Effect on Hand Function (ULNART)

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

Coronary angiography and angioplasty are commonly performed through the radial artery at the wrist as this approach is associated with fewer bleeding complications and faster recovery. In some patients, the radial artery becomes occluded after prior procedures, requiring selection of an alternative access site for future coronary interventions. The ulnar artery is a potential alternative wrist access. However, limited data are available on the safety of using the ulnar artery in the same arm as an occluded radial artery and on the possible effects on hand strength, sensation, and daily hand function. The goal of this observational study is to evaluate the safety of transulnar access and its effect on hand function in adults with ipsilateral radial artery occlusion undergoing coronary angiography or angioplasty. The main questions addressed by the study are: * How often do serious access-related vascular or nerve complications occur? * Does hand strength, sensation, or functional use of the hand change during follow-up? * Does the ulnar artery remain patent after the procedure? The choice of vascular access site is made by the treating physician based on clinical judgment. Participants who undergo transulnar access will undergo follow-up assessments, including ultrasound evaluation of arm arteries, standardized hand function testing, and short questionnaires assessing upper-limb function. The findings of this study are expected to inform access-site selection, improve patient counseling, and support safer care for patients with radial artery occlusion undergoing coronary procedures.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

⁃ Participants must meet all of the following criteria to be eligible:

• Adults aged 18 years or older

• Documented radial artery occlusion in the upper limb intended for vascular access, confirmed by ultrasound or angiography

• Scheduled to undergo elective coronary angiography and/or angioplasty

• Transulnar arterial access on the same side as the occluded radial artery is selected by the treating physician

• Contralateral radial artery access is not feasible or is clinically undesirable, including for reasons such as:

• documented occlusion or severe disease of the contralateral radial artery

• unfavorable anatomy or prior failed access

• strategic preservation of the contralateral radial artery for future surgical or dialysis needs

• Adequate ulnar artery flow and anatomy for access, as assessed by pre-procedural ultrasound

• Able and willing to provide written informed consent

Locations
Other Locations
Greece
Hellenic Red Cross Hospital
RECRUITING
Athens
Hippokratio General Hospital
RECRUITING
Athens
Contact Information
Primary
Dimitrios Karelas, MD
dim.f.karelas@gmail.com
+30 698 6428463
Backup
Konstantinos Aznaouridis, Ass. Professor of Cardiology
conazna@yahoo.com
+30 697 2024534
Time Frame
Start Date: 2025-11-01
Estimated Completion Date: 2032-01
Participants
Target number of participants: 127
Treatments
ULNART Cohort
Adults with documented radial artery occlusion undergoing elective coronary angiography or angioplasty, in whom transulnar arterial access ipsilateral to the occluded radial artery is selected by the treating physician. Participants are followed prospectively to assess vascular safety and hand function outcomes.
Related Therapeutic Areas
Sponsors
Leads: National and Kapodistrian University of Athens

This content was sourced from clinicaltrials.gov