• Patient age is ≥18 years

• Patient agrees to participate and to comply with the protocol by signing an IRB approved patient consent form

• Patient is able to walk unassisted or with non-motorized assistive devices

• Patient has PAD with documented Rutherford Class 2-4 of the target limb

• Anticipated life expectancy \>12 months, in the opinion of the investigator at the time of enrollment.

⁃ Angiographic Inclusion Criteria:

• Patient has de novo atherosclerotic disease of the native SFA and/or the popliteal arteries

• Target lesion has ≥70% diameter stenosis by investigator via visual assessment

• Target lesion length ≤150mm. Total treatment zone may not exceed 150mm, and may include one or more lesions.

• Chronic total occlusion lesion length is \<100mm of the total ≤150mm target lesion

• Minimum reference vessel diameter (RVD) 4.0mm by visual estimate

• Target lesion crossed and intraluminal guidewire placement confirmed; successful crossing defined as tip of the guidewire distal to the target lesion in the absence of flow limiting dissections or perforations

• At least one patent tibial vessel (defined as \<50% stenosis) with runoff to the foot

• Target lesion has moderate to severe calcification graded using the Peripheral Academic Research Consortium (PARC) criteria