• Age 22 to 75 years (inclusive) at the time of enrollment.

• Diagnosis of radiculopathy and/or myelopathy of the cervical spine, with pain, paresthesias or paralysis in a specific nerve root distribution C3 through C7, including at least one of the following:

‣ Neck and/or arm pain (at least 3 on the 0 - 10 numeric rating scale for pain.

⁃ Decreased muscle strength of at least one level on the clinical evaluation 0 to 5 scale.

⁃ Abnormal sensation including hyperesthesia or hypoesthesia. and/or

⁃ Abnormal reflexes.

• Symptomatic at one or two contiguous levels from C3 to C7.

• Radiographically determined pathology at the level to be treated correlating to primary symptoms including at least one of the following:

‣ Decreased disc height on radiography, computed tomography (CT), or magnetic resonance imaging (MRI) in comparison to a normal adjacent disc.

⁃ Degenerative spondylosis on CT or MRI.

⁃ Disc herniation on CT or MRI.

• Neck Disability Index Score ≥ 30/100.

• Unresponsive to non-operative treatment (e.g., rest, heat, physical therapy, chiropractor, massage, pain medication) for approximately six weeks from the symptom onset; or has the presence of progressive symptoms or signs of nerve root/spinal cord compression in the face of continued non-operative management.

• No previous surgical intervention at the involved levels or any subsequent, planned/staged surgical procedure at the involved or adjacent levels.

• Appropriate for treatment using an anterior surgical approach.

• Skeletally mature at the time of the surgery.

⁃ Medically cleared for surgery.

⁃ If a female of child-bearing potential, subject is non-pregnant, nonnursing, and agrees not to become pregnant during the study period.

⁃ Willing and able to comply with the study plan.

⁃ Signed written Patient Informed Consent Form.

⁃ Willing to discontinue use of non-steroidal anti-inflammatory drugs (NSAIDs) from one week before the surgery to 3 months after the surgery.