Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors
Status: Recruiting
Location: See all (3) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This randomized clinical trial is evaluating the impact of a positive psychology intervention (PATH) on anxiety symptoms, depression symptoms, and quality of life in survivors of hematopoietic stem cell transplant (HSCT) compared to usual care.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Adult patients (aged 18 years and older) undergoing allogeneic HSCT and are approaching 100-days post-HSCT
• Ability to speak, read, and respond to questions in English or Spanish to complete study procedures
• Access to a basic telephone
Locations
United States
Florida
Moffitt Cancer Center
RECRUITING
Tampa
Massachusetts
Dana Farber Cancer Institute
RECRUITING
Boston
North Carolina
Duke Cancer Institute
RECRUITING
Durham
Contact Information
Primary
Hermioni Amonoo, MD, MPP, MPH
hermioni_amonoo@dfci.harvard.edu
617-525-7472
Backup
Isabella Larizza, BSc
ilarizza@bwh.harvard.edu
Time Frame
Start Date: 2024-12-17
Estimated Completion Date: 2030-05-31
Participants
Target number of participants: 400
Treatments
Experimental: Positive Affect in the Transplantation of Hematopoietic Stem Cells (PATH)
Participants recruited from the Dana-Farber Cancer Institute, Duke Cancer Institute, and Moffitt Cancer Center who are randomized to the intervention/experimental arm will receive the PATH intervention, which is focused on gratitude, strengths, and meaning, as well as focused exercises on goal-setting and tracking daily physical activity.~Participants will complete questionnaires (in person, over the computer or telephone, or by mail) at predetermined days per protocol.
No_intervention: Usual Care
Participants recruited from the Dana-Farber Cancer Institute, Duke Cancer Institute, and Moffitt Cancer Center who are randomized to the usual care arm will receive their usual support from the HSCT team, including all routine supportive care resources (e.g., support from social work) offered by the HSCT team.~Participants will complete questionnaires (in person, over the computer or telephone, or by mail) at predetermined days per protocol.
Related Therapeutic Areas
Sponsors
Leads: Brigham and Women's Hospital
Collaborators: Dana-Farber Cancer Institute, Duke University, H. Lee Moffitt Cancer Center and Research Institute