The Impact of GLP-1 Agonist and GIP Agonist on Bowel Preparation Quality: A Randomized Controlled Trial

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn how GLP-1 and GIP agonists effect bowel preparation in patients scheduled for colonoscopies. The main questions it aims to answer are: * Does GLP-1 and GIP agonist increase the rate of inadequate bowel preparation? * Does the quality of bowel preparation differ in patients who hold vs. those who continue a single dose of their GLP-1 or GIP agonist medication? * Are there any differences in the rates of complications gastric aspiration in patients who hold vs. continue a single dose of their GLP-1 or GIP agonist medication?

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Adult patient (Age 18 years or older)

• Patient scheduled for outpatient screening, surveillance, or diagnostic colonoscopy

• Using a GLP-1 or GIP agonist at a stable dose for at least one month

Locations
United States
Florida
Cleveland Clinic
RECRUITING
Cleveland
Cleveland Clinic Weston
RECRUITING
Weston
Time Frame
Start Date: 2025-08
Estimated Completion Date: 2026-08
Participants
Target number of participants: 120
Treatments
Active_comparator: Continue GLP/GIP medication
Patient maintains dose, frequency, duration of medication prior to colonoscopy.
No_intervention: Hold medication
Withholds prior dose of GLP-1 or GIP therapy per ASA guidance recommendations
Related Therapeutic Areas
Sponsors
Leads: The Cleveland Clinic

This content was sourced from clinicaltrials.gov

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