Colonoscopy Clinical Trials

Clinical trials related to Colonoscopy Procedure

Comparison of Three Different Rescue Bowel Preparation Regimens in Patients With Previous Bowel Cleansing Failure at Colonoscopy

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn which rescue bowel preparation works best for adults who need a repeat colonoscopy after a previous bowel preparation did not clean the bowel well enough. The study will also look at how satisfied participants are with each preparation. The main questions it aims to answer are: * Which bowel preparation helps more participants achieve adequate bowel cleansing before repeat colonoscopy? * Which bowel preparation leads to better cleansing in different parts of the colon? * Which bowel preparation is better tolerated by participants? Researchers will compare 3 rescue bowel preparation regimens to see which one works best for repeat colonoscopy after a previous cleansing failure. Participants will: * be randomly assigned to 1 of 3 bowel preparation regimens * take one of the following regimens before repeat colonoscopy: * 4 liters of polyethylene glycol (PEG) plus 12 milligrams of bisacodyl * 1 liter of PEG plus ascorbic acid plus 10 milligrams of bisacodyl * 2 liters of PEG plus extra PEG taken over the 3 days before colonoscopy * undergo repeat colonoscopy * rate their satisfaction with the bowel preparation

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adults aged 18 years or older

• Prior inadequate bowel preparation (adequately performed) requiring repeat colonoscopy

• Scheduled to undergo repeat outpatient colonoscopy

• Ability to provide informed consent

Locations
Other Locations
Italy
San Pio Hospital
RECRUITING
Benevento
Contact Information
Primary
Giuseppe Scaglione
giuseppe.scaglione@aornsanpio.it
+39 360638237
Time Frame
Start Date: 2024-01-02
Estimated Completion Date: 2026-06
Participants
Target number of participants: 220
Treatments
Active_comparator: 4 L PEG + bisacodyl
Participants receive 4 L polyethylene glycol (PEG) plus bisacodyl 12 mg before repeat colonoscopy after prior inadequate bowel preparation.
Active_comparator: 1 L PEG plus ascorbic acid + bisacodyl
Participants receive 1 L polyethylene glycol (PEG) plus ascorbic acid and bisacodyl 10 mg before repeat colonoscopy after prior inadequate bowel preparation.
Active_comparator: 2 L PEG + additional PEG
Participants receive 2 L polyethylene glycol (PEG) plus additional PEG administered during the 3 days before repeat colonoscopy after prior inadequate bowel preparation.
Related Therapeutic Areas
Sponsors
Leads: Ospedale San Pio

This content was sourced from clinicaltrials.gov