Colonoscopy Clinical Trials

Clinical trials related to Colonoscopy Procedure

The Value of Early Postoperative Colonoscopy in The Early Diagnosis of Anastomotic Leakage After Surgery for Low Colorectal Cancer:A Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn whether early postoperative colonoscopy is valuable in the early diagnosis of anastomotic leakage after surgery for low colorectal cancer.The main questions it aims to answer are: 1. Will the median diagnosis time of AL in the intervention group (early colonoscopy group) be significantly shorter than that in the control group? 2. Can targeted treatment (such as endoscopic vacuum therapy (EVT)) be initiated earlier in the early colonoscopy group, thereby reducing the incidence of AL and the rate of unplanned re-laparotomy? Researchers will compare the median diagnosis time of AL in the intervention group (early colonoscopy group) with the control group to observe whether early postoperative colonoscopy can detect anastomotic leakage earlier. Participants will: Experimental group (early colonoscopy group): 1. Colonoscopy will be performed on the 5th to 8th day after surgery (the surgeon will decide the specific date within this time window based on the patient's recovery). 2. Carry out adequate intestinal preparation before the examination (the specific plan is formulated according to the hospital's routine, which may involve antegrade or retrograde enema, etc., and needs to be recorded and standardized). Control group (routine observation group): 1. Receive standard postoperative management, including monitoring vital signs, abdominal signs, drainage fluid properties, etc. 2. Only when clinical symptoms suspected of anastomotic leakage occur (such as persistent fever, worsening abdominal pain, turbid drainage fluid or stool samples), CT scan, gastrointestinal angiography or diagnostic colonoscopy should be performed according to clinical indications.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Age 18-80 years old.

• Pathologically diagnosed as colorectal adenocarcinoma.

• The distance between the lower edge of the tumor and the anal verge is ≤15cm.

• Accept laparoscopic or open radical resection and complete primary colorectal or colosal anastomosis.

• Voluntarily participate and sign the written informed consent.

Locations
Other Locations
China
Beijing Anzhen Hospital Nanchong Hospital Affiliated to Capital Medical University
RECRUITING
Nanchong
Contact Information
Primary
Yunhong Tian, Doctor
drtianyunhong@126.com
86+13508087719
Time Frame
Start Date: 2026-04-30
Estimated Completion Date: 2027-06-30
Participants
Target number of participants: 140
Treatments
Experimental: Experimental group (early colonoscopy group)
No_intervention: Control group (routine observation group)
Related Therapeutic Areas
Sponsors
Leads: Nanchong Central Hospital

This content was sourced from clinicaltrials.gov