Effect of an Individualized Non-pharmacological Intervention Based on a Predictive Model for Inadequate Bowel Preparation on Bowel Preparation Quality: a Three-arm, Prospective, Randomized Controlled Study
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Colonoscopy is essential for the early detection of colorectal cancer. However, inadequate bowel preparation remains a common challenge, associated with reduced adenoma detection rates, prolonged procedure time, and increased healthcare costs. Current individualized regimens rely largely on higher laxative dosages-an approach with limited clinical utility. Non-pharmacological interventions, including dietary modification, physical activity, and health education, are safe and tend to have better patient adherence. The effectiveness of health education depends largely on message framing. Guided by information-framing theory, we developed an individualized non-pharmacological regimen. This randomized controlled trial aims to evaluate the efficacy of this regimen in improving bowel preparation quality.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• age ≥ 18 years;
• outpatient scheduled for colonoscopy using oral laxatives for bowel preparation;
• able to understand the study and provide written informed consent.
Locations
Other Locations
China
General Hospital of Northern Theater Command
RECRUITING
Shenyang
Contact Information
Primary
Xingshun Qi
xingshunqi@126.com
+8618909881019
Backup
weiyi wang
373302698@qq.com
13019441021
Time Frame
Start Date:2026-06-08
Estimated Completion Date:2026-09-30
Participants
Target number of participants:339
Treatments
Active_comparator: Standard bowel preparation group
Patients receive verbal instructions and printed text-based bowel preparation education materials, along with a standard bowel preparation regimen.
Experimental: Individualized bowel preparation group
Patients receive verbal instructions and printed illustrated bowel preparation educational materials. The inadequate bowel preparation risk score is calculated using the established prediction model. Patients with a risk score ≥ 3.25 receive an enhanced bowel preparation regimen, whereas those with a score \< 3.25 receive the standard bowel preparation regimen. The enhanced bowel preparation regimen is based on the standard protocol, with two additional components. First, starting 3 days before the colonoscopy, patients are instructed to avoid high-fiber foods and, from 1 day before the colonoscopy, to adopt a semiliquid low-residue diet. They are also asked to walk for 30 minutes after each meal, with a target of approximately 6,000 steps per day. Second, after consuming each 500 mL of the polyethylene glycol electrolyte solution and upon finishing the entire solution, patients are asked to chew one piece of sugar-free gum for 10 minutes.
Experimental: Information-framing guided individualized bowel preparation group
Patients receive the same interventions as those in the individualized group. In addition, they receive information-framed educationa material. For those with an inadequate bowel preparation risk score ≥ 3.25, negatively-framed materials emphasizing the harms of non-adherence are provided; for those with a score \< 3.25, positively-framed materials emphasizing the benefits of adherence are provided.