Outcomes of Uretheroileal Suspension Technique During Open Radical Cystectomy and Ileal Neobladder: A Prospective Randomized Comparative Study

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The suspension technique is reported as the puboprostatic ligaments that attach the prostate to the symphysis pubis. After the ligating the complex, including both the dorsal vein complex and the puboprostatic ligaments, this complex was sharply divided anteriorly from the prostate with a safe distance (1-2 mm), and the urethra is defined and divided. After removing the prostate, the ileal pouch is reconstructed by completely everting the mucosa and sutured outward with a running 4-0 absorbable suture around the edge. The neck of the neobladder was narrowed to ≈1 cm, for convenient passage of a 20 F catheter. Anastomotic sutures of 3-0 absorbable polyglactin were placed at the 1, 3, 5, 6, 7, 9, 11 and 12 o'clock positions

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Patient age \>18 years.

• Muscle-invasive bladder carcinoma (MIBC).

• Non-muscle-invasive bladder carcinoma (NMIBC) fulfilling the following criteria:

‣ \- (recurrent disease that is unresponsive to other treatments

⁃ \- high-grade tumors (T1, carcinoma in situ) refractory to intravesical therapy

⁃ -Multifocal or recurrent high-grade tumors despite intravesical therapy and the tumor progression from NMIBC to MIBC).

Locations
Other Locations
Egypt
Sohag University Hospital
RECRUITING
Sohag
Contact Information
Primary
abdelrahman m abdellah, assistant lecturer
abdelrahman.ahmed1@med.shag.edu.eg
+201014649841
Backup
ahmed m mohamed, lecturer
Time Frame
Start Date: 2025-01-01
Estimated Completion Date: 2027-01-01
Participants
Target number of participants: 60
Treatments
Active_comparator: : group (A) 30 patients will be treated with suspension uretheroileal technique
Active_comparator: group (B) 30 patients will be treated with conventional radical cystectomy and ileal neobladder
Related Therapeutic Areas
Sponsors
Leads: Sohag University

This content was sourced from clinicaltrials.gov