Corticostriatal Neurophysiology in Parkinson's Disease Cognitive Impairment
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this study is to learn more about the brain activity underlying Parkinson's disease cognitive impairment. The investigators will utilize neural recordings from corticostriatal structures performed during deep brain stimulation surgery to measure neural activity underlying nonmotor symptoms of Parkinson's disease.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: f
View:
• Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center
• Planned clinical electrode trajectory that contacts caudate
• Age greater than or equal to 40
• Diagnosis of Parkinson's disease
• Able to participate in intraoperative testing
• English speaking
Locations
United States
Tennessee
Vanderbilt University Medical Center
RECRUITING
Nashville
Contact Information
Primary
Isabel Long, BS
isabel.long@vumc.org
615-421-3046
Backup
Sarah Bick, MD
Sarah.Bick@vumc.org
615-343-9822
Time Frame
Start Date: 2021-06-02
Estimated Completion Date: 2026-02
Participants
Target number of participants: 75
Treatments
Experimental: Neural recordings and stimulation
Related Therapeutic Areas
Sponsors
Leads: Vanderbilt University Medical Center