Efficacy of Pain Intervention With Deep Brain Stimulation Neuromodulation
The goal of this clinical trial is to learn if deep brain stimulation (DBS) works to treat severe pain following a stroke in adults. It will also learn about the safety of deep brain stimulation. The main questions it aims to answer are: * Does DBS lower the pain score in these participants. * What medical problems do participants have when having DBS? Researchers will compare different settings, to see if DBS works to treat severe post stroke pain. Participants will: * Undergo baseline screening procedures and have an MRI scan. * Have neurosurgery to put the DBS system in * Have follow up for 10 months * Visit the clinic at least 5 times in the study for check-ups and tests * Fill in questionnaires about pain and mood and have check ups remotely
⁃ A patient will be eligible for inclusion in this trial if all of the following criteria apply:
• Willing and able to give informed consent for participation in the trial.
• Willing and able to follow pre and post-operative procedures in Oxford.
• Aged 21 years or above.
• Diagnosed as having central post stroke pain of 2 years' minimum duration refractory to best medical/non-medical treatment
• Mean usual VAS (or NRS) pain score \> 6/10 despite input from a multidisciplinary pain team.