Deep Brain Stimulation Clinical Trials

Clinical trials related to Deep Brain Stimulation Procedure

Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this study is to understand the development and progression of childhood dystonia, a movement disorder, in children. The main questions it aims to answer are: How does the activity of the neural network evolve in children with dystonia in the context of motor development? What are the effects of chronic and active stimulation on cortical and subcortical motor network function in children with deep brain stimulation (DBS)? Participants will: * Undergo noninvasive electrophysiological measurements (EEG, EMG) to quantify neural network activity. They will be tested at rest and during a simple motor reaction task. * Children with DBS will be assessed in the on and off DBS state to assess effects of chronic and active changes in motor network function.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 6
Maximum Age: 21
Healthy Volunteers: t
View:

• For dystonia subjects:

• Dx of dystonia (with and without DBS)

• willingness and ability to complete study protocols.

• For Typically Developing Controls:

• normal developmental milestones

• absence of any neuropsychiatric disorder

• no significant medical condition.

Locations
United States
Ohio
Cincinnati Children's Hospital Medical Center
RECRUITING
Cincinnati
Time Frame
Start Date: 2024-01-01
Estimated Completion Date: 2029-12-31
Participants
Target number of participants: 75
Treatments
Experimental: DBS
Patients with DBS will complete neurophysiological recordings with DBS on and off
Sponsors
Leads: Children's Hospital Medical Center, Cincinnati

This content was sourced from clinicaltrials.gov