Best Dose of Magnesium Sulfate Infusion in Obese. A Blind and Randomized Trial

Who is this study for? Patients with Obesity
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other, Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

Magnesium sulfate has been shown to be a successful tool in a large number of clinical areas. Its benefits include neuroprotection, control of eclampsia / pre-eclampsia, control of intraoperative blood pressure, decreased neuroendocrine response during laryngoscopy and tracheal intubation and reduced levels of postoperative pain and consumption of analgesic. Obese patients have become more and more frequent in the operating rooms, due to the increasing prevalence of this population worldwide. However, although they have received magnesium sulfate as part of the analgesic strategy in many centers, there has been no study demonstrating the appropriate dose of this medication in obese patients. This study aims to compare two doses of magnesium sulfate in obese patients: based on their real weight or based on ideal weight.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:

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Locations
Other Locations
Brazil
Sebastião Ernesto Silva Filho
NOT_YET_RECRUITING
São José Dos Campos
Hospital das Clínicas - Faculdade de Medicina da Universidade de Sao Paulo
RECRUITING
São Paulo
Contact Information
Primary
sebastião silva filho
sebasernesto@gmail.com
12991457764
Time Frame
Start Date: 2022-04-01
Estimated Completion Date: 2025-12-01
Participants
Target number of participants: 75
Treatments
Placebo_comparator: Lactate ringer group
Patients will receive only general anesthesia
Active_comparator: Real weight group
Patients who will receive general anesthesia and magnesium sulfate infused at a dose of 15 mg.kg-1.h-1 based on the actual body weight
Active_comparator: Corrected ideal weight group
Patients who will receive general anesthesia and magnesium sulfate infused at a dose of 15 mg.kg-1.h-1 based on the corrected ideal weight
Sponsors
Leads: University of Sao Paulo General Hospital

This content was sourced from clinicaltrials.gov

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