Pain Managment After VATS to Reduce Postoperative Pain and Improve Pulmonary Function

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Thoracic surgery is now common and as other surgeries evolution of minimally invasive techniques is employed. Video-assisted thoracic surgery (VATS) produces little scar but may produce severe pain that may affect the pulmonary function. Many procedure was developed like intercostal nerve block which require injections at multiple levels, Insertion of local anaesthetic (LA) in the surgical drain but that was dangerous due to the large amount of LA and not sufficient to completely eliminate pain. Bupvicaine nebulization, through surgical port which won't make any other wound, thought to be sufficient because Nebulization will enable us better distribution and less amounts of LA. Bupvicaine is local anaesthetic amide group that works by blocking sodium channels thus preventing progression of action potential.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Patients that reach American socity of anesthesiologist class 1-3

• Scheduled for VATS surgery under general anesthesia.

Locations
Other Locations
Egypt
Assiut University
RECRUITING
Asyut
Contact Information
Primary
Esam Moubarak Sahin
Emobarak94@gmail.com
01094878158
Time Frame
Start Date: 2024-05-17
Estimated Completion Date: 2024-07-15
Participants
Target number of participants: 60
Treatments
Experimental: Intrapleural bupivacine nebulization
Intrapleural nebulization of bupivacine (10 ml of bupivacaine 0.5%) + Intravenous normal saline as a placebo
Active_comparator: Intravenous paracetamol and ketorolac
Intravenous analgesia: paracetamol (one gram) and Ketorolac (30 mg) + Intrapleural normal saline (10 ml) as a placebo
Related Therapeutic Areas
Sponsors
Leads: Assiut University

This content was sourced from clinicaltrials.gov