Evaluating Optimal Perioperative Pain Management: A Prospective Randomized Control Trial of Laparoscopic Transversus Abdominis Plane Block With Local Anesthetic, Laparoscopic Transversus Abdominis Plane Block Alone, and Local Anesthetic Alone in Minimally Invasive Oncologic Surgery

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery. This project is considered Research and participation is voluntary. Upon enrollment in this study, the research team will collect data from the patient's medical records. The patient will undergo all of the normal testing and procedures required pre-operatively (standard of care). The study team will then randomly assign the patient (like a flip of a coin) to one of three different study arms for pain management during surgery: 1. Laparoscopic Transversus Abdominis Plane Block (LapTAP) with Local Anesthetic (LA) 2. Laparoscopic Transversus Abdominis Plane Block (LapTAP) only 3. Local Anesthetic (LA) only The patient will receive standard pre- and post-operative care according to clinical guidelines (routine care). The study team will collect information from the patient's medical record for the first 24 hours after their surgery and upon discharge. This information will include pain scores, amount of medication required, any side effects the patient may have experienced, and satisfaction with pain control. Participation in the study will end upon discharge from the hospital.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 89
Healthy Volunteers: f
View:

• Male and female patients age ≥ 18 - 89

• Patients scheduled for elective (clinically indicated) hepatic, gastric, biliary, pancreatic, gynecologic, colorectal, other GI Minimally invasive oncologic surgery.

• Patients who have provided informed consent to participate in the study.

• Patients with an American Society of Anesthesiologists (ASA) physical status classification of I, II, or III.

• Patients undergoing procedures anticipated to last more than 1 hour but less than 8 hours.

• Patients able to understand and self-report pain using the designated pain Visual Analog Scale

Locations
United States
Pennsylvania
AHN West Penn Hospital
RECRUITING
Pittsburgh
Contact Information
Primary
Casey Allen, MD
casey.allen@ahn.org
(412) 913-6466
Backup
AHN Clinical Trials Contact
clinicaltrials@ahn.org
412-913-6466
Time Frame
Start Date: 2025-02-05
Estimated Completion Date: 2026-12
Participants
Target number of participants: 48
Treatments
Active_comparator: Laparoscopic Transversus Abdominis Plane Block with Local Anesthetic
Patient would be receiving Laparoscopic Transversus Abdominis Plane block in addition to Local Anesthetic per standard of care.
Active_comparator: Laparoscopic Transversus Abdominis Plane block only
Patient would be receiving Laparoscopic Transversus Abdominis Plane block without Local Anesthetic per standard of care.
Active_comparator: Local Anesthetic only
Patient would be receiving Local Anesthetic per standard of care.
Sponsors
Leads: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

This content was sourced from clinicaltrials.gov

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